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alpha Adducin 抗体 (pThr445)

This anti-alpha Adducin antibody is a 兔 多克隆 antibody detecting alpha Adducin in ELISA, IHC (p), IF (cc), IF (p), ICC 和 IHC (fro). Suitable for 人.
产品编号 ABIN1713941
发货至: 中国

Quick Overview for alpha Adducin 抗体 (pThr445) (ABIN1713941)

抗原

See all alpha Adducin (ADD1) 抗体
alpha Adducin (ADD1) (Adducin 1 (Alpha) (ADD1))

适用

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宿主

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克隆类型

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多克隆

标记

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This alpha Adducin antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

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    pThr445

    预测反应

    Human,Mouse,Rat

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human alpha Adducin around the phosphorylation site of Thr445

    亚型

    IgG
  • 应用备注

    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    alpha Adducin (ADD1) (Adducin 1 (Alpha) (ADD1))

    别名

    alpha Adducin

    背景

    Synonyms: Adducin phospho T445, p-Adducin phospho T445, ADD1, ADDA, Adducin 1 alpha, Adducin 1, Alpha adducin, ADDA_HUMAN.

    Background: Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha and beta adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha and gamma adducins are ubiquitously expressed. In contrast, beta adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca2+/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms, however, not all variants have been fully described.

    基因ID

    118

    UniProt

    P35611

    途径

    Negative Regulation of Hormone Secretion, Regulation of Actin Filament Polymerization, Regulation of Lipid Metabolism by PPARalpha, ER-Nucleus Signaling
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