IRF6 抗体 (AA 1-100)
Quick Overview for IRF6 抗体 (AA 1-100) (ABIN1713852)
抗原
See all IRF6 抗体适用
宿主
克隆类型
标记
应用范围
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    - 
                                            抗原表位
- AA 1-100
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                                            交叉反应
- 人, 小鼠
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                                            预测反应
- Rat,Cow,Sheep,Pig,Rabbit
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                                            纯化方法
- Purified by Protein A.
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                                            免疫原
- KLH conjugated synthetic peptide derived from human IRF6
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                                            亚型
- IgG
 
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                                            应用备注
- 
                        WB 1:300-5000
 ELISA 1:500-1000
 dot-blot()
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                                            限制
- 仅限研究用
 
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    - 
                                            状态
- Liquid
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                                            浓度
- 1 μg/μL
- 
                                            缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 
                                            储存液
- ProClin
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                                            注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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                                            储存条件
- 4 °C,-20 °C
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                                            储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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                                            有效期
- 12 months
 
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    - IRF6 (Interferon Regulatory Factor 6 (IRF6))
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                                            别名
- IRF6
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                                            背景
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                        Synonyms: Interferon regulatory factor 6, IRF 6, IRF-6, IRF6, IRF6_HUMAN, LPS, OFC 6, OFC6, OTTHUMP00000034677, OTTHUMP00000034678, PIT, PPS, PPS1, VWS, VWS1. Background: Interferon regulatory factor-1 (IRF-1) and IRF-2 have been identified as novel DNA-binding factors that function as regulators of both type I interferon (interferon-alpha and beta) and interferon-inducible genes. The two factors are structurally related, particularly in their N-terminal regions, which confer DNA binding specificity. In addition, both bind to the same sequence within the promoters of interferon-alpha and interferon-beta genes. IRF-1 functions as an activator of interferon transcription, while IRF-2 binds to the same cis elements and represses IRF-1 action. IRF-1 and IRF-2 have been reported to act in a mutually antagonistic manner in regulating cell growth, overexpression of the repressor IRF-2 leads to cell transformation while concomitant overexpression of IRF-1 causes reversion. IRF-1 and IRF-2 are members of a larger family of DNA binding proteins that includes IRF-3, IRF-4, IRF-5, IRF-6, IRF-7, ISGF-3 gamma p48 and IFN consensus sequence-binding protein (ICSBP). 
 抗原
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