GPR17 抗体 (AA 2-100)
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北京 101111
Quick Overview for GPR17 抗体 (AA 2-100) (ABIN1713795)
抗原
See all GPR17 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2-100
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预测反应
- Human
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human G protein coupled receptor 17
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亚型
- IgG
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anti-G Protein-Coupled Receptor 17 (GPR17) (C-Term) antibody
Verified GPR17 适用: 人, 小鼠 WB, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 17 (GPR17) (AA 1-36) antibodyGPR17 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 17 (GPR17) (Cytoplasmic Domain) antibodyGPR17 适用: 人, Cow, 马, 猴, Pig, 兔 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 17 (GPR17) (AA 230-258) antibodyGPR17 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB24874 unconjugated
anti-G Protein-Coupled Receptor 17 (GPR17) (AA 237-266), (Middle Region) antibodyGPR17 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 17 (GPR17) antibodyGPR17 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 17 (GPR17) (AA 220-232), (Intracellular) antibodyGPR17 适用: 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- GPR17 (G Protein-Coupled Receptor 17 (GPR17))
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别名
- GPR17
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背景
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Synonyms: DKFZp686M18273, G protein coupled receptor 17, G-protein coupled receptor 17, GPR 17, Gpr17, GPR17_HUMAN, P2Y like receptor, P2Y-like receptor, Probable P2Y purinoceptor GPR 17, Probable P2Y purinoceptor GPR17, R12, UDP/CysLT receptor, Uracil nucleotide/cysteinyl leukotriene receptor, GPCR GPR17.
Background: G protein-coupled receptor 17, GPR17, also known as uracil nucleotide/cysteinyl leukotriene receptor or P2Y-like receptor (P2YL), is a 367 amino acid member of the G-protein coupled receptor 1 family of proteins. While GPR17 is expressed in kidney, heart and umbilical vein endothelial cells, it is expressed in the highest levels in the brain. Upon brain injury, the extracellular concentrations of nucleotides and cysteinyl leukotrienes (CysLTs), two families of endogenous signaling molecules, increase significantly at the site of damage. In some neurons, GPR17, a membrane receptor for uracil nucleotide and CysLTs, is upregulated as well, infiltrating the lesioned area. GPR17 is thought to play a role in mediating neuronal death, remodeling brain circuitries by microglia and initiating remyelination in damaged neurons. Two named isoforms of GPR17 exist as a result of alternative splicing events.
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基因ID
- 2840
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UniProt
- Q13304
抗原
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