GPR17 抗体 (Intracellular, Loop 3)
Our Local Distributor
北京 101111
Quick Overview for GPR17 抗体 (Intracellular, Loop 3) (ABIN7043149)
抗原
See all GPR17 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 220-232, Intracellular, Loop 3
-
原理
- A Rabbit Polyclonal Antibody to GPR17 Receptor
-
交叉反应
- 小鼠, 大鼠
-
交叉反应 （详细）
- Not recommended for human samples.
-
预测反应
- Mouse - identical
-
产品特性
- Anti-GPR17 Antibody (ABIN7043149, ABIN7044435 and ABIN7044436) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot and immunohistochemistry applications. It has been designed to recognize GPR17 from rat and mouse samples. It is unlikely to recognize the protein from human samples.
-
纯化方法
- Affinity purified on immobilized antigen.
-
免疫原
- (C)RQGPRIEKHLKNK, corresponding to amino acid residues 220-232 of rat GPR17
-
亚型
- IgG
-
-
anti-G Protein-Coupled Receptor 17 (GPR17) (C-Term) antibody
Verified GPR17 适用: 人, 小鼠 WB, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 17 (GPR17) (AA 230-258) antibodyGPR17 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB24874 unconjugated
anti-G Protein-Coupled Receptor 17 (GPR17) (AA 1-36) antibodyGPR17 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 17 (GPR17) (Cytoplasmic Domain) antibodyGPR17 适用: 人, Cow, 马, 猴, Pig, 兔 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-G Protein-Coupled Receptor 17 (GPR17) (AA 237-266), (Middle Region) antibodyGPR17 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
WB: 1:200
FC: The optimal concentration should be determined by the user
ICC: The optimal concentration should be determined by the user
IHC: 1:300
IP: The optimal concentration should be determined by the user
-
说明
-
Negative Control: (ABIN7235376)
Blocking Peptide: (ABIN7235376)
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.
-
浓度
- 0.8 mg/mL
-
缓冲液
- PBS pH 7.4, 1 % BSA with 0.05 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C
-
-
- GPR17 (G Protein-Coupled Receptor 17 (GPR17))
-
别名
- GPR17
-
背景
-
Synonyms: G-protein coupled receptor 17, Uracil nucleotide/cysteinyl leukotriene receptor, UDP/CysLT Receptor, P2Y-like receptor
Description: GPR17 is an orphan receptor that can be double-activated by uracil and cysteinyl-leukotriene (CysLT). It is phylogenetically related to both purinergic P2Y and CysLT receptors. GPR17 belongs to the superfamily of G-protein coupled receptors (GPCRs)4.GPR17 expression is highly detected in the brain, kidney, and heart. In the brain, GPR17 is mainly distributed in white matter, gray matter, subependymal zone, and corpus callosum1.Studies have shown that GPR17 receptor plays an important role in spinal cord injury, myelin sheath injury, cerebral ischemic injury, where its expression is extremely upregulated1,2.GPR17 activation promotes oligodendrocyte differentiation and progression toward mature myelin-forming cells. Thus, GPR17 modulators may be used as therapeutic tools to treat pathologies associated with myelin repair in CNS demyelinating diseases3.
-
基因ID
- 767613
-
NCBI登录号
- NM_001161415
-
UniProt
- Q09QM4
抗原
-
