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FZD6 抗体 (AA 11-110)

This anti-FZD6 antibody is a 兔 多克隆 antibody detecting FZD6 in WB, ELISA, ICC, IHC (p), IF (cc), IF (p) 和 IHC (fro). Suitable for 小鼠 和 大鼠.
产品编号 ABIN1713791
发货至: 中国

Quick Overview for FZD6 抗体 (AA 11-110) (ABIN1713791)

抗原

See all FZD6 抗体
FZD6 (Frizzled Family Receptor 6 (FZD6))

适用

  • 38
  • 12
  • 6
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
小鼠, 大鼠

宿主

  • 36
  • 2
  • 2
  • 2

克隆类型

  • 39
  • 3
多克隆

标记

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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This FZD6 antibody is un-conjugated

应用范围

  • 27
  • 15
  • 9
  • 6
  • 6
  • 5
  • 4
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 8
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 11-110

    交叉反应

    小鼠, 大鼠

    预测反应

    Human

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Frizzled 6

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    FZD6 (Frizzled Family Receptor 6 (FZD6))

    别名

    Frizzled 6

    背景

    Synonyms: FZ6, FZ-6, HFZ6, NDNC10, Frizzled-6, FZD6

    Background: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.

    基因ID

    8323

    UniProt

    O60353

    途径

    WNT signaling, Tube Formation
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