FZD6 抗体 (AA 11-110)
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北京 101111
Quick Overview for FZD6 抗体 (AA 11-110) (ABIN1713791)
抗原
See all FZD6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 11-110
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交叉反应
- 小鼠, 大鼠
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预测反应
- Human
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Frizzled 6
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亚型
- IgG
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anti-Frizzled Family Receptor 6 (FZD6) (C-Term) antibody
FZD6 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 6 (FZD6) (N-Term) antibodyFZD6 适用: 人, 猴 IHC, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 6 (FZD6) antibodyFZD6 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 6 (FZD6) (AA 19-201) antibodyFZD6 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 6 (FZD6) (AA 539-588) antibodyFZD6 适用: 人, 大鼠, 猴, Cow, 犬, 豚鼠, 马, Pig, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 6 (FZD6) (AA 116-165) antibodyFZD6 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Frizzled Family Receptor 6 (FZD6) (Extracellular Domain), (N-Term) antibodyFZD6 适用: 人 IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- FZD6 (Frizzled Family Receptor 6 (FZD6))
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别名
- Frizzled 6
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背景
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Synonyms: FZ6, FZ-6, HFZ6, NDNC10, Frizzled-6, FZD6
Background: Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
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基因ID
- 8323
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UniProt
- O60353
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途径
- WNT signaling, Tube Formation
抗原
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