LIMA1 抗体 (AA 161-260)
Quick Overview for LIMA1 抗体 (AA 161-260) (ABIN1713685)
抗原
See all LIMA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 161-260
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预测反应
- Human,Mouse,Dog,Cow,Sheep,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human EPLIN
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亚型
- IgG
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anti-LIM Domain and Actin Binding 1 (LIMA1) (AA 1-598) antibody
LIMA1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1B7 unconjugated
anti-LIM Domain and Actin Binding 1 (LIMA1) (N-Term) antibodyLIMA1 适用: 人, 小鼠, 大鼠, 兔, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain and Actin Binding 1 (LIMA1) (C-Term) antibodyLIMA1 适用: 人, 小鼠, 大鼠, 兔, 马, Cow, 斑马鱼, 猴, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain and Actin Binding 1 (LIMA1) (C-Term) antibodyLIMA1 适用: 人, 小鼠, 大鼠, 兔, 马, Cow WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain and Actin Binding 1 (LIMA1) (AA 143-192) antibodyLIMA1 适用: 人, 小鼠, 兔, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain and Actin Binding 1 (LIMA1) (AA 502-551) antibodyLIMA1 适用: 人, 小鼠, 兔, Cow, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain and Actin Binding 1 (LIMA1) (AA 560-759) antibodyLIMA1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-LIM Domain and Actin Binding 1 (LIMA1) (Middle Region) antibodyLIMA1 适用: 人, 小鼠, 大鼠, 兔, 马, Cow, 犬, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- LIMA1 (LIM Domain and Actin Binding 1 (LIMA1))
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别名
- EPLIN
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背景
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Synonyms: 1110021C24Rik, Epithelial protein lost in neoplasm, Epithelial protein lost in neoplasm beta, EPLIN, FLJ38853, LIM domain and actin binding 1, LIM domain and actin binding protein 1, LIM domain and actin-binding protein 1, LIMA1, LIMA1_HUMAN, MGC131726, SREBP3, Sterol regulatory element binding protein 3.
Background: Epithelial protein lost in neoplasm (EPLIN) is a cytoskeleton-associated protein characterized by the presence of a single centrally located lin-11, isl-1 and mec-3 (LIM) domain. It also contains at least two Actin-binding domains, in which the C-terminal domain binds more effectively than the N-terminal domain. By binding Actin monomers and filaments, EPLIN is involved in regulation of the Actin cytoskeleton by increasing the number and size of Actin stress fibers, delaying filament nucleation, reducing formation of branched filaments and bundling of Actin filaments. It also inhibits membrane ruffling and Actin filament depolymerization. EPLIN is strongly expressed in placenta, kidney, pancreas, prostate, ovary, spleen and heart, and to a lesser degree in lung, liver, brain, skeletal muscle, thymus, testis and intestine. It is expressed as two isoforms, EPLIN- and EPLIN-_. Downregulation of EPLIN- expression may contribute to the motility of invasive tumor cells.
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基因ID
- 51474
抗原
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