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FFAR1 抗体 (PE-Cy5)

This PE-Cy5-conjugated 兔 多克隆 anti-FFAR1 antibody specifically detects FFAR1 in WB. The antibody is reactive with 人, 小鼠, 大鼠, 犬 和 Pig samples.
产品编号 ABIN1713024
发货至: 中国
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for FFAR1 抗体 (PE-Cy5) (ABIN1713024)

抗原

See all FFAR1 抗体
FFAR1 (Free Fatty Acid Receptor 1 (FFAR1))

适用

  • 55
  • 29
  • 15
  • 4
  • 4
  • 3
  • 1
人, 小鼠, 大鼠, 犬, Pig

宿主

  • 55
  • 1

克隆类型

  • 56
多克隆

标记

  • 22
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This FFAR1 antibody is conjugated to PE-Cy5

应用范围

  • 42
  • 17
  • 13
  • 13
  • 8
  • 6
  • 5
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB)
  • 交叉反应

    人, 小鼠

    预测反应

    Rat,Dog,Pig

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human GPR40

    亚型

    IgG
  • 应用备注

    FCM(1:100-500)
    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    FFAR1 (Free Fatty Acid Receptor 1 (FFAR1))

    别名

    GPR40

    背景

    Synonyms: FFA1R, GPR40, GPCR40, Free fatty acid receptor 1, G-protein coupled receptor 40, FFAR1

    Background: G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis. Fatty acid binding increases glucose-stimulated insulin secretion, and may also enhance the secretion of glucagon-like peptide 1 (GLP-1). May also play a role in bone homeostasis, receptor signaling activates pathways that inhibit osteoclast differentiation (By similarity). Ligand binding leads to a conformation change that triggers signaling via G-proteins that activate phospholipase C, leading to an increase of the intracellular calcium concentration. Seems to act through a G(q) and G(i)-mediated pathway.

    基因ID

    2864

    UniProt

    O14842

    途径

    Positive Regulation of Peptide Hormone Secretion, Hormone Transport, Peptide Hormone Metabolism, Carbohydrate Homeostasis
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