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Betacellulin 抗体 (PE-Cy5)

This 兔 多克隆 antibody specifically detects Betacellulin in WB. It exhibits reactivity toward 人.
产品编号 ABIN1712935
发货至: 中国
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Quick Overview for Betacellulin 抗体 (PE-Cy5) (ABIN1712935)

抗原

See all Betacellulin (BTC) 抗体
Betacellulin (BTC)

适用

  • 49
  • 35
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  • 1

宿主

  • 67
  • 6
  • 1
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克隆类型

  • 70
  • 5
多克隆

标记

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  • 1
  • 1
  • 1
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This Betacellulin antibody is conjugated to PE-Cy5

应用范围

  • 66
  • 22
  • 20
  • 13
  • 13
  • 10
  • 8
  • 8
  • 6
  • 4
  • 3
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Western Blotting (WB)
  • 交叉反应

    小鼠

    预测反应

    Human

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Betacellulin

    亚型

    IgG
  • 应用备注

    FCM(1:100-500)
    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    Betacellulin (BTC)

    别名

    Beta cellulin

    背景

    Synonyms: Beta cellulin, Beta cellulin precursor, BTC, BTC_HUMAN, OTTHUMP00000160600, OTTHUMP00000219057, Probetacellulin.

    Background: Betacellulin (BTC), a member of the epidermal growth factor (EGF) family, was originally identified as a growth-promoting factor in the conditioned medium of a mouse pancreatic-cell carcinoma (insulinoma) cell line and has since been identified in humans. BTC is synthesized as a large transmembrane precursor molecule that can be cleaved proteolytically to release the soluble form of BTC or function as membrane-anchored growth factors in juxtacrine signaling. BTC, in addition to stimulating homodimers of ErbB-1 and ErbB-4, is capable of binding and activating all possible combinations of heterodimeric ErbB receptors including the oncogenic ErbB-2/ErbB-3 complex. BTC is also expressed in some human malignancies and may have an important role in tumor growth progression.

    基因ID

    685

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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