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TYROBP 抗体 (PE)

TYROBP 适用: 人 FACS 宿主: 兔 Polyclonal PE
产品编号 ABIN1712671
发货至: 中国
  • 抗原 See all TYROBP 抗体
    TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))
    适用
    • 51
    • 20
    • 4
    宿主
    • 68
    • 1
    • 1
    克隆类型
    • 61
    • 9
    多克隆
    标记
    • 20
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    This TYROBP antibody is conjugated to PE
    应用范围
    • 39
    • 29
    • 26
    • 26
    • 18
    • 15
    • 12
    • 6
    • 3
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human DAP12
    亚型
    IgG
    Top Product
    Discover our top product TYROBP Primary Antibody
  • 应用备注
    FCM(1:20-100)
    说明

    Exitation/Emission: 480,565nm/578nm

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at 4°C
    有效期
    12 months
  • 抗原
    TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))
    别名
    Dap12 (TYROBP 产品)
    背景

    This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70 kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL. Multiple alternative transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Mar 2010]

    Subcellular location: Extracellular


    Synonyms: DAP 12, DAP12, DNAX activation protein 12, DNAX-activation protein 12, KAR-associated protein, KARAP, Killer activating receptor associated protein, Killer-activating receptor-associated protein, PLOSL, TYOBP_HUMAN, TYRO protein tyrosine kinase binding protein, TYRO protein tyrosine kinase-binding protein, TYROBP.
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