Ataxin 1 抗体 (pSer775) (HRP)
Quick Overview for Ataxin 1 抗体 (pSer775) (HRP) (ABIN1711760)
抗原
See all Ataxin 1 (ATXN1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer775
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic phosphopeptide derived from human Ataxin 1 around the phosphorylation site of Ser776
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亚型
- IgG
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anti-Ataxin 1 (ATXN1) (AA 645-815) antibody
ATXN1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 4C7B11 unconjugated
anti-Ataxin 1 (ATXN1) antibodyATXN1 适用: 人 IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 2F5 unconjugated
anti-Ataxin 1 (ATXN1) (AA 645-815) antibodyATXN1 适用: 人, 小鼠 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 2B8A2 unconjugated
anti-Ataxin 1 (ATXN1) (AA 569-807) antibodyATXN1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 1 (ATXN1) (C-Term) antibodyATXN1 适用: 人, 小鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 1 (ATXN1) (AA 331-587) antibodyATXN1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 1 (ATXN1) (AA 346-475) antibodyATXN1 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ataxin 1 (ATXN1) (AA 746-761) antibodyATXN1 适用: 小鼠 WB, IF, ICC 宿主: 小鼠 Monoclonal S65-37 unconjugated
anti-Ataxin 1 (ATXN1) (AA 164-197) antibodyATXN1 适用: 小鼠 WB, IHC, IF, IP, ICC 宿主: 小鼠 Monoclonal S76-8 unconjugated
anti-Ataxin 1 (ATXN1) (AA 164-197) antibody (HRP)ATXN1 适用: 小鼠 WB, IHC, IF, IP, ICC 宿主: 小鼠 Monoclonal S76-8 HRP
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应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- Ataxin 1 (ATXN1)
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别名
- Ataxin 1
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背景
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Synonyms: Ataxin 1 phospho S776,p-Ataxin 1 phospho S776, ATX1, ATXN1, SCA1, Ataxin 1, Ataxin-1, Ataxin1, Spinocerebellar ataxia type 1, ATX1_HUMAN.
Background: Ataxin-1, also designated spinocerebellar ataxia type 1 protein (Sca-1), is differentially expressed and localizes to both the cytoplasm and the nucleus. Mutations in Ataxin-1 are associated with the onset of the autosomal dominant neurodegenerative disorder spinocerebellar ataxia type 1 (SCA-1), which is characterized by progressive neuronal loss in the cerebellum, muscle wasting and ataxia. In Purkinje cells, where SCA-1 is predominantly observed, Ataxin-1 has been shown to directly associate with the Purkinje-enriched leucine-rich acidic nuclear protein (LANP) and the nuclear matrix-associated protein promyelocytic leukemia protein PML. In SCA-1, Ataxin-1 is mutated to encode a polyglutamine protein that forms nuclear aggregates, which interact significantly more strongly with LANP and contribute to the pathogenesis of SCA-1.
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基因ID
- 6310
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途径
- Synaptic Membrane
抗原
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