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GC-Rich Promoter Binding Protein 1 (GPBP1) (AA 11-110) 抗体 (HRP)

This anti- antibody is a 兔 多克隆 antibody detecting in WB, ELISA, IHC (p) 和 IHC (fro). Suitable for 小鼠.
产品编号 ABIN1711707
发货至: 中国

Quick Overview for GC-Rich Promoter Binding Protein 1 (GPBP1) (AA 11-110) 抗体 (HRP) (ABIN1711707)

抗原

See all GC-Rich Promoter Binding Protein 1 (GPBP1) 抗体
GC-Rich Promoter Binding Protein 1 (GPBP1)

适用

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小鼠

宿主

  • 22

克隆类型

  • 22
多克隆

标记

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HRP

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 14
    • 3
    • 1
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    AA 11-110

    交叉反应

    小鼠

    预测反应

    Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human GPBP1/Vasculin

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    注意事项

    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    GC-Rich Promoter Binding Protein 1 (GPBP1)

    别名

    GPBP1/Vasculin

    背景

    Synonyms: DKFZp761C169, GC rich promoter binding protein 1, GC-rich promoter-binding protein 1, GPBP, Gpbp1, GPBP1_HUMAN, MGC126339, SSH6, Vascular wall linked, Vascular wall-linked protein, Vasculin.

    Background: Vascular wall-linked protein, or Vasculin, is primarily expressed in the arterial wall and in plasma. It is also differentially expressed in human atherogenesis. Alternative splicing of exon 3 of the Vasculin gene produces three variants. Vasculin binds to and activates the minimal self-sufficient promoter element (MSPE) of the mouse Ada gene promoter and binds to and partially suppresses the GC-rich promoter of the nonhomologous human TOP2A gene promoter. It acts as a nuclear factor that can form complexes with TATA-binding proteins, transcription factors TFIIB and TFIIF, RNA polymerase II and p300. The regulated expression of Vasculin in plaques suggests that it may be involved in atherogenesis, and its presence in plasma may implicate Vasculin as a marker for atherosclerosis.

    基因ID

    65056
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