GAPVD1 抗体 (AA 1151-1250) (HRP)
Quick Overview for GAPVD1 抗体 (AA 1151-1250) (HRP) (ABIN1711513)
抗原
See all GAPVD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1151-1250
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预测反应
- Human,Mouse,Rat,Cow,Sheep,Horse,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human GAPVD1
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亚型
- IgG
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应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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注意事项
- Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- GAPVD1 (GTPase Activating Protein and VPS9 Domains 1 (GAPVD1))
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别名
- GAPVD1
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背景
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Synonyms: GAPEX 5, GAPVD1, GTPase activating protein and VPS9 domains 1, KIAA1521, Rab5 activating protein 6, RAP6, GAPD1_HUMAN.
Background: GAPVD1 is a 1478 amino acid peripheral membrane protein that acts both as a GTPase-activating protein (GAP) and a guanine nucleotide exchange factor (GEF). GAPVD1 participates in many processes such as insulin receptor internalization, Glut4 trafficking and endocytosis. In addition, depletion of GAPVD1 leads to delayed EGFR degradation by mediating receptor ubiquination through its RGD domain, suggesting that it may be an important mediator of carcinogenesis resulting from Ras protein mutations. There are six isoforms of GAPVD1 that are produced as a result of alternative splicing events.
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基因ID
- 26130
抗原
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