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FLT3 抗体 (pTyr599) (FITC)

Name: FLT3 抗体 (pTyr599) (FITC)
SKU: ABIN1709974
Availability: OutOfStock

This FITC-conjugated 兔多克隆 anti-FLT3 antibody specifically detects FLT3 in WB, IF (cc) 和 IF (p). The antibody is reactive with 人 samples.

产品编号 ABIN1709974

发货至: 中国

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中国
北京 101111

No. 88 KeChuang 6th Street

Beijing Economic Technological Development Area

Room 801-803

4A Biotech Co.,Ltd.

Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for FLT3 抗体 (pTyr599) (FITC) (ABIN1709974)

抗原

See all FLT3 抗体

FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))

适用

人

宿主

兔

克隆类型

多克隆

标记

This FLT3 antibody is conjugated to FITC

应用范围

Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Discover our top product FLT3 Primary Antibody

抗原表位
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pTyr599

交叉反应

人

预测反应

Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit,Guinea Pig

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic phosphopeptide derived from human FLT3 around the phosphorylation site of Tyr599

亚型

IgG
anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 930-991) antibody
FLT3 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 7B7C3 unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 62-295) antibody
FLT3 适用: 小鼠, 大鼠 WB, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) antibody
FLT3 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 334-543) antibody
FLT3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 335-544) antibody
FLT3 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 33-64) antibody
FLT3 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) (AA 650-750) antibody
FLT3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) (C-Term) antibody
FLT3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated

anti-Fms-Related tyrosine Kinase 3 (FLT3) antibody (FITC)
FLT3 适用: 人 FACS 宿主: 小鼠 Monoclonal BV10A4 FITC

anti-Fms-Related tyrosine Kinase 3 (FLT3) antibody (PE)
FLT3 适用: 人 FACS 宿主: 小鼠 Monoclonal BV10A4 PE

应用备注

IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

有效期

12 months
抗原

FLT3 (Fms-Related tyrosine Kinase 3 (FLT3))

别名

FLT3

背景

Synonyms: Receptor-type tyrosine-protein kinase FLT3, FL cytokine receptor, Fetal liver kinase-2, FLK-2, Fms-like tyrosine kinase 3, FLT-3, Stem cell tyrosine kinase 1, STK-1, FLT3, CD135, FLK2, STK1
Background: Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1, and activation of the downstream effector MTOR. Promotes activation of RAS signaling and phosphorylation of downstream kinases, including MAPK1/ERK2 and/or MAPK3/ERK1. Promotes phosphorylation of FES, FER, PTPN6/SHP, PTPN11/SHP-2, PLCG1, and STAT5A and/or STAT5B. Activation of wild-type FLT3 causes only marginal activation of STAT5A or STAT5B. Mutations that cause constitutive kinase activity promote cell proliferation and resistance to apoptosis via the activation of multiple signaling pathways.

基因ID

2322

途径

RTK signaling