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alpha Adducin 抗体 (pSer436) (FITC)

This FITC-conjugated 兔 多克隆 anti-alpha Adducin antibody specifically detects alpha Adducin in WB, IF (p) 和 IF (cc). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN1709779
发货至: 中国
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Quick Overview for alpha Adducin 抗体 (pSer436) (FITC) (ABIN1709779)

抗原

See all alpha Adducin (ADD1) 抗体
alpha Adducin (ADD1) (Adducin 1 (Alpha) (ADD1))

适用

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人, 小鼠, 大鼠

宿主

  • 90
  • 3

克隆类型

  • 89
  • 3
多克隆

标记

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This alpha Adducin antibody is conjugated to FITC

应用范围

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Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
  • 抗原表位

    • 17
    • 15
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    • 6
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    • 4
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    • 2
    • 2
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    • 1
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    • 1
    • 1
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    • 1
    pSer436

    交叉反应

    人, 小鼠, 大鼠

    预测反应

    Dog,Cow,Horse,Chicken

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human alpha Adducin around the phosphorylation site of Ser436

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    alpha Adducin (ADD1) (Adducin 1 (Alpha) (ADD1))

    别名

    alpha Adducin

    背景

    Synonyms: alpha Adducinphospho S436, alpha Adducinphospho Ser436, p-alpha AdducinS436, p-alpha AdducinSer436, ADD 1, ADD A, ADD1, ADD1 protein, ADDA, ADDA_HUMAN, Adducin 1 alpha, Adducin 1 alpha, Alpha adducin, Alpha-adducin, Erythrocyte adducin alpha subunit, Erythrocyte hosphor subunit alpha, Erythrocyte adducin subunit alpha.

    Background: Adducins are a family of cytoskeleton proteins encoded by three genes (Alpha, Beta, Gamma). Adducin is a protein associated with the inner leaflet of the plasma membrane and is one of the proteins localized at the spectrin-actin junction of the membrane skeleton. The cortical actin cytoskeletal network is lost during apoptosis and Adducins are central in the cortical actin network organization. Adducin Alpha is a cytoskeletal protein involved with sodium-pump activity in the renal tubule and is associated with hypertension. The expression of Adducin Alpha and Adducin Gamma is ubiquitous in contrast to the restricted expression of Adducin Beta. Adducin Beta is expressed at high levels in brain and hematopoietic tissues, such as bone marrow, in humans, and in spleen in mice.

    基因ID

    118

    途径

    Negative Regulation of Hormone Secretion, Regulation of Actin Filament Polymerization, Regulation of Lipid Metabolism by PPARalpha, ER-Nucleus Signaling
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