RUSC1 抗体 (AA 281-380) (FITC)
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北京 101111
Quick Overview for RUSC1 抗体 (AA 281-380) (FITC) (ABIN1709593)
抗原
See all RUSC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 281-380
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交叉反应
- 人, 小鼠
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预测反应
- Rat,Cow,Sheep,Pig
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human RUSC1
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亚型
- IgG
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anti-RUN and SH3 Domain Containing 1 (RUSC1) (AA 1-320) antibody
RUSC1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-RUN and SH3 Domain Containing 1 (RUSC1) (AA 231-433) antibodyRUSC1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-RUN and SH3 Domain Containing 1 (RUSC1) (AA 1-433) antibodyRUSC1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- RUSC1 (RUN and SH3 Domain Containing 1 (RUSC1))
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别名
- Rusc1
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背景
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Synonyms: DKFZp761A1822, Nesca, New molecule containing SH3 at the carboxy terminus, RUN and SH3 domain containing 1, RUN and SH3 domain containing protein 1, RUSC 1.
Background: RUSC1 is a 902 amino acid protein that contains a RUN domain and a SH3 domain. RUSC1?s RUN domain is necessary for NGF induced nuclear redistribution. RUSC1 is a putative signaling adapter which may play a role in neuronal differentiation. RUSC1 seems to be involved in signaling pathways that are regulated by the prolonged activation of MAPK. RUSC2 (RUN and SH3 domain containing 2), also known as Iporin, is a 1,516 amino acid cytoplasmic protein that is widely expressed, with highest levels in brain and testis. The RUN domain of RUSC2 is required for interaction with Rab 1A, Rab 1B and GM130. It is thought that RUSC2 may possibly function as a connector between endoplasmic reticulum (ER) derived vesicle targets triggered by the Rab 1 GTPases and a signaling pathway regulated by molecules containing SH3 and/or poly-proline regions. RUSC2 also consists of a SH3 domain, suggesting a role in protein-protein interactions.
抗原
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