DKC1 抗体 (AA 81-190) (Cy7)
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- 抗原 See all DKC1 抗体
- DKC1 (Dyskeratosis Congenita 1, Dyskerin (DKC1))
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抗原表位
- AA 81-190
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DKC1 antibody is conjugated to Cy7
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human Dyskerin
- 亚型
- IgG
- Top Product
- Discover our top product DKC1 Primary Antibody
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anti-Dyskeratosis Congenita 1, Dyskerin (DKC1) (AA 245-514) antibody
DKC1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dyskeratosis Congenita 1, Dyskerin (DKC1) antibodyDKC1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Dyskeratosis Congenita 1, Dyskerin (DKC1) antibodyDKC1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dyskeratosis Congenita 1, Dyskerin (DKC1) (AA 1-514) antibodyDKC1 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Dyskeratosis Congenita 1, Dyskerin (DKC1) (AA 1-180) antibodyDKC1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dyskeratosis Congenita 1, Dyskerin (DKC1) (AA 1-514) antibodyDKC1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E10 unconjugated
anti-Dyskeratosis Congenita 1, Dyskerin (DKC1) (AA 94-170) antibodyDKC1 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Dyskeratosis Congenita 1, Dyskerin (DKC1) (Internal Region) antibodyDKC1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dyskeratosis Congenita 1, Dyskerin (DKC1) (AA 298-465) antibodyDKC1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Dyskeratosis Congenita 1, Dyskerin (DKC1) (AA 298-509) antibodyDKC1 适用: 小鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- DKC1 (Dyskeratosis Congenita 1, Dyskerin (DKC1))
- 别名
- Dyskerin (DKC1 产品)
- 别名
- CBF5 antibody, DKC antibody, DKCX antibody, NAP57 antibody, NOLA4 antibody, XAP101 antibody, dyskerin antibody, fv62a07 antibody, wu:fa28f10 antibody, wu:fc87a02 antibody, wu:fi24a05 antibody, wu:fv62a07 antibody, zgc:110395 antibody, DKC1 antibody, cbf5 antibody, dkc antibody, nap57 antibody, nola4 antibody, xap101 antibody, BC068171 antibody, Nap57 antibody, AtCBF5 antibody, AtNAP57 antibody, homologue of NAP57 antibody, dyskerin pseudouridine synthase 1 antibody, microRNA 664b antibody, dyskeratosis congenita 1, dyskerin antibody, dyskeratosis congenita 1, dyskerin L homeolog antibody, homologue of NAP57 antibody, DKC1 antibody, MIR664B antibody, dkc1 antibody, dkc1.L antibody, Dkc1 antibody, NAP57 antibody
- 背景
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Synonyms: CBF5, CBF5 homolog, Cbf5p homolog, DKC 1, DKC, Dkc1, DKC1_HUMAN, DKCX, Dyskeratosis congenita 1, Dyskeratosis congenita 1 dyskerin, Dyskerin, H/ACA ribonucleoprotein complex subunit 4, NAP 57, NAP57, NAP-57, NOLA 4, NOLA4, Nopp140 associated protein of 57 kDa, Nopp140-associated protein of 57 kDa, Nucleolar protein family A member 4, Nucleolar protein NAP57, snoRNP protein DKC1, XAP 101, XAP101.
Background: Dyskerin (NAP57) associates with the chaperone protein Nopp140 and forms a small ribonucleoprotein particle with GAR1 (NOLA1), NHP2 (NOLA2) and Nop10 for the isomerization of uridine to pseudouridine (1). GAR1, NHP2 and dyskerin localize to the dense fibrillar component of the nucleolus and in nuclear Cajal bodies (2). The dyskerin gene maps to chromosome Xq28 (3). Missense mutations in the dyskerin gene interfere with normal nuclear localization of dyskerin and cause Dyskeratosis congenita (DKC) (4). DKC is a rare, X-linked bone marrow disorder characterized by cutaneous hyperpigmentation, dystrophy of the nails, atrophy of the testicles and leukoplakia of the oral mucosa. The GAR1 gene maps to chromosome 4q25 (5,6). The NHP2 gene maps to chromosome 5q35.3 and encodes a 155-amino acid protein (2,7).
- 基因ID
- 1736
- 途径
- Telomere Maintenance
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