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IRF6 抗体 (Cy7)

This anti-IRF6 antibody is a 兔 多克隆 antibody detecting IRF6 in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN1707743
发货至: 中国

Quick Overview for IRF6 抗体 (Cy7) (ABIN1707743)

抗原

See all IRF6 抗体
IRF6 (Interferon Regulatory Factor 6 (IRF6))

适用

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  • 6
  • 6
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  • 6
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  • 1
人, 小鼠, 大鼠

宿主

  • 67
  • 8
  • 1

克隆类型

  • 61
  • 15
多克隆

标记

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  • 2
  • 1
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This IRF6 antibody is conjugated to Cy7

应用范围

  • 51
  • 16
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  • 9
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  • 1
  • 1
Western Blotting (WB)
  • 交叉反应

    人, 小鼠

    预测反应

    Rat,Cow,Sheep,Pig,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human IRF6

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    IRF6 (Interferon Regulatory Factor 6 (IRF6))

    别名

    Irf6

    背景

    Synonyms: Interferon regulatory factor 6, IRF 6, IRF-6, IRF6, IRF6_HUMAN, LPS, OFC 6, OFC6, OTTHUMP00000034677, OTTHUMP00000034678, PIT, PPS, PPS1, VWS, VWS1.

    Background: Interferon regulatory factor-1 (IRF-1) and IRF-2 have been identified as novel DNA-binding factors that function as regulators of both type I interferon (interferon-alpha and beta) and interferon-inducible genes. The two factors are structurally related, particularly in their N-terminal regions, which confer DNA binding specificity. In addition, both bind to the same sequence within the promoters of interferon-alpha and interferon-beta genes. IRF-1 functions as an activator of interferon transcription, while IRF-2 binds to the same cis elements and represses IRF-1 action. IRF-1 and IRF-2 have been reported to act in a mutually antagonistic manner in regulating cell growth, overexpression of the repressor IRF-2 leads to cell transformation while concomitant overexpression of IRF-1 causes reversion. IRF-1 and IRF-2 are members of a larger family of DNA binding proteins that includes IRF-3, IRF-4, IRF-5, IRF-6, IRF-7, ISGF-3 gamma p48 and IFN consensus sequence-binding protein (ICSBP).

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