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ADRM1 抗体 (AA 21-120) (Cy5.5)

This anti-ADRM1 antibody is a 兔 多克隆 antibody detecting ADRM1 in IF (cc) 和 IF (p). Suitable for 人.
产品编号 ABIN1706566
发货至: 中国

Quick Overview for ADRM1 抗体 (AA 21-120) (Cy5.5) (ABIN1706566)

抗原

See all ADRM1 (Adrm1) 抗体
ADRM1 (Adrm1) (Adhesion Regulating Molecule 1 (Adrm1))

适用

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宿主

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克隆类型

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多克隆

标记

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This ADRM1 antibody is conjugated to Cy5.5

应用范围

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Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
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    AA 21-120

    预测反应

    Human,Mouse,Rat,Dog,Cow,Sheep

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human ADRM1

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    ADRM1 (Adrm1) (Adhesion Regulating Molecule 1 (Adrm1))

    别名

    ADRM1

    背景

    Synonyms: 110 kDa cell membrane glycoprotein, adhesion regulating molecule 1, Adhesion-regulating molecule 1, ADRM 1, Adrm1, ADRM1_HUMAN, ARM 1, ARM-1, ARM1, GP110, hRpn13, Mr 110,000 surface antigen, Proteasomal ubiquitin receptor ADRM1, proteasome regulatory particle non ATPase 13, Proteasome regulatory particle non-ATPase 13, Regulatory particle non ATPase 13, Rpn13, Rpn13 homolog.

    Background: ADRM1 is a 407 amino acid protein that localizes to both the nucleus and the cytoplasm and is thought to be involved in protein recruitment and cell adhesion. An integral membrane protein, ADRM1 functions to recruit UCH-L5, a deubiquitinating enzyme, to the 26S proteasome, and once at the proteasome it promotes the activity of UCH-L5. Additionally, ADRM1 is thought to mediate lymphocyte adhesion in endothelial cells and may thus play a role in lymphocyte homing. ADRM1 expression is induced by IFN-g in some cancer cell lines and its expression is upregulated in other metastatic cells, suggesting a role in carcinogenesis. Two isoforms of ADRM1 exist due to alternative splicing events.

    基因ID

    11047

    途径

    Positive Regulation of Endopeptidase Activity
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