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G6PC3 抗体 (AA 201-300) (Cy5.5)

This anti-G6PC3 antibody is a 兔 多克隆 antibody detecting G6PC3 in WB 和 IF (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN1706452
发货至: 中国

Quick Overview for G6PC3 抗体 (AA 201-300) (Cy5.5) (ABIN1706452)

抗原

See all G6PC3 抗体
G6PC3 (Glucose 6-Phosphatase, Catalytic 3 (G6PC3))

适用

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人, 小鼠, 大鼠

宿主

  • 19

克隆类型

  • 19
多克隆

标记

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This G6PC3 antibody is conjugated to Cy5.5

应用范围

  • 18
  • 12
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Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 1
    • 1
    • 1
    • 1
    AA 201-300

    交叉反应

    人, 小鼠, 大鼠

    预测反应

    Cow,Sheep,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human G6PC3

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    G6PC3 (Glucose 6-Phosphatase, Catalytic 3 (G6PC3))

    别名

    G6PC3

    背景

    Synonyms: G-6-Pase 3, G6Pase 3, G6Pase-beta, Glucose 6 phosphatase, catalytic, 3, Glucose-6-phosphatase 3, Glucose-6-phosphatase beta, SCN4, Ubiquitous glucose-6-phosphatase catalytic subunit-related protein, UGRP,

    Background: Glucose-6-phosphatase (G6Pase), is a multicomponent enzyme system that hydrolyzes glucose-6-phosphate (G6P) in the final step of gluconeogenesis and gluconeolysis. G6Pase localizes to the endoplasmic reticulum, and while liver, kidney, and intestine are the only tissues that express the first identified isoform, G6Pase-Alpha, a second form, designated G6Pase-Beta, contributes to blood glucose homeostasis in a wider range of tissues. G6Pase-Beta, also known as SCN4, UGRP or G6PC3 (glucose 6 phosphatase, catalytic, 3), is a 346 amino acid endoplasmic reticulum multi-pass membrane protein that is involved in carbohydrate biosynthesis and the gluconeogenesis pathway. Inhibited by vanadate, G6Pase-Beta hydrolyzes GP6 to glucose in the endoplasmic reticulum. Due to its necessary involvement in normal glucose metabolism, G6Pase-Beta may play an integral role in diabetes and glycogen storage diseases (GSDs).

    基因ID

    92579

    UniProt

    Q9BUM1
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