GADL1 抗体 (AA 51-150) (Cy5.5)
Quick Overview for GADL1 抗体 (AA 51-150) (Cy5.5) (ABIN1705734)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 51-150
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预测反应
- Human,Mouse,Rat,Bee
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human GADL1
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亚型
- IgG
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anti-Glutamate Decarboxylase-Like 1 (GADL1) (AA 215-264) antibody
GADL1 适用: 人, 小鸡, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Glutamate Decarboxylase-Like 1 (GADL1) (Middle Region) antibodyGADL1 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- GADL1 (Glutamate Decarboxylase-Like 1 (GADL1))
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别名
- GADL1
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背景
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Synonyms: GADL1, GADL1_HUMAN, Glutamate decarboxylase like 1, Glutamate decarboxylase-like protein 1, MGC138191, OTTHUMP00000161199, OTTHUMP00000222306.
Background: There are two forms of glutamic acid decarboxylases (GADs) that exist in brain: GAD-65 (also known as GAD2) and GAD-67 (also known as GAD1, GAD or SCP). GAD-65 and GAD-67 are members of the group II decarboxylase family of proteins and are responsible for catalyzing the rate limiting step in the production of GABA (gamma-aminobutyric acid) from L-glutamic acid. Although both GADs are found in brain, GAD-65 localizes to synaptic vesicle membranes in nerve terminals, while GAD-67 is distributed throughout the cell. GAD-67 is responsible for the basal levels of GABA synthesis. In the case of a heightened demand for GABA in neurotransmission, GAD-65 transiently activates to assist in GABA production. As a member of the group II decarboxylase family, GADL1 (Glutamate decarboxylase-like protein 1) is a 521 amino acid protein that utilizes pyridoxal phosphate as a cofactor for its carboxylase activity. There are two isoforms of GADL1 that exist as a result of alternative splicing events.
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基因ID
- 339896
抗原
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