Dnmt2 抗体 (AA 61-160) (Cy5)
Quick Overview for Dnmt2 抗体 (AA 61-160) (Cy5) (ABIN1705119)
抗原
See all Dnmt2 (TRDMT1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 61-160
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预测反应
- Human,Mouse,Rat,Cow,Sheep,Pig
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Dnmt2
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亚型
- IgG
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anti-tRNA Aspartic Acid Methyltransferase 1 (TRDMT1) (AA 1-391) antibody
TRDMT1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-tRNA Aspartic Acid Methyltransferase 1 (TRDMT1) (AA 1-391) antibodyTRDMT1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1E12 unconjugated
anti-tRNA Aspartic Acid Methyltransferase 1 (TRDMT1) (AA 170-269) antibodyTRDMT1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-tRNA Aspartic Acid Methyltransferase 1 (TRDMT1) (AA 346-375) antibodyTRDMT1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB1850 unconjugated
anti-tRNA Aspartic Acid Methyltransferase 1 (TRDMT1) (AA 346-375) antibodyTRDMT1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-tRNA Aspartic Acid Methyltransferase 1 (TRDMT1) (AA 201-230) antibodyTRDMT1 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-tRNA Aspartic Acid Methyltransferase 1 (TRDMT1) antibodyTRDMT1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-tRNA Aspartic Acid Methyltransferase 1 (TRDMT1) antibodyTRDMT1 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-tRNA Aspartic Acid Methyltransferase 1 (TRDMT1) (AA 72-121) antibodyTRDMT1 适用: 人, 小鼠, 大鼠, Cow, 犬, Pig, 兔, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-tRNA Aspartic Acid Methyltransferase 1 (TRDMT1) (AA 1-391) antibodyTRDMT1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- Dnmt2 (TRDMT1) (tRNA Aspartic Acid Methyltransferase 1 (TRDMT1))
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别名
- Dnmt2
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背景
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Synonyms: dDNMT, D mMT 2, D mMT2, DNA cytosine 5 methyltransferase 2, DNA cytosine 5 methyltransferase like protein 2, DNA cytosine-5-methyltransferase-like protein 2, DNA 5 cytosine methyltransferase, DNA methyltransferase 2, DNA methyltransferase homolog HsaIIP, DNA MTase homolog HsaIIP, Dnmt 2, Dnmt2, M.HsaIIP, MHsaIIP, nmt 2, nmt2, OTTHUMP00000045198, PuMet, RNMT 1, RNMT1, TRDMT 1, TRDMT_HUMAN, TRDMT1, tRNA cytosine 5 methyltransferase, tRNA cytosine38-C5-methyltransferase, tRNA aspartic acid methyltransferase 1, tRNA aspartic acid methyltransferase 1 variant 1, tRNA aspartic acid methyltransferase 1 variant 2, tRNA aspartic acid methyltransferase 1 variant 3, tRNA aspartic acid methyltransferase 1 variant 4, tRNA aspartic acid methyltransferase 1 variant 5, tRNA aspartic acid methyltransferase 1 variant 8.
Background: Methylation at the 5'-position of cytosine is the only known naturally occurring covalent modification of the mammalian genome. DNA methylation requires the enzymatic activity of DNA 5-cytosine methyltransferase (Dnmt) proteins, which catalyze the transfer of a methyl group from S-adenosyl methionine to the 5'-position of cytosines residing in the dinucleotide CpG motif, and this methylation results in transcriptional repression of the target gene. The Dnmt enzymes are encoded by independent genes. Dnmt1 is the most abundant, and it preferentially methylates hemimethylated DNA and coordinates gene expression during development. Additional mammalian Dnmt proteins include Dnmt2 and Dnmt3. Dnmt2 lacks the large N-terminal regulator domain of Dnmt1, is expressed at substantially lower levels in adult tissues, and is likely involved in methylating newly integrated retroviral DNA. Dnmt3a and Dnmt3b are encoded by two distinct genes, but both are abundantly expressed in embryonic stem cells, where they also methylate CpG motifs on DNA.
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基因ID
- 1787
抗原
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