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HHATL 抗体 (AA 25-125) (Cy5)

This anti-HHATL antibody (ABIN1704952) is a Rabbit Polyclonal antibody detecting HHATL in WB, IF (cc), IF (p). Suitable for Human.
产品编号 ABIN1704952
发货至: 中国

Quick Overview for HHATL 抗体 (AA 25-125) (Cy5) (ABIN1704952)

抗原

See all HHATL 抗体
HHATL (Hedgehog Acyltransferase-Like (HHATL))

适用

  • 17
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宿主

  • 16
  • 1

克隆类型

  • 16
  • 1
多克隆

标记

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This HHATL antibody is conjugated to Cy5

应用范围

  • 16
  • 12
  • 12
  • 5
  • 5
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 2
    • 1
    AA 25-125

    预测反应

    Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human HHATL/GUP1

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    HHATL (Hedgehog Acyltransferase-Like (HHATL))

    别名

    HHATL/GUP1

    背景

    Synonyms: C3orf3, Glycerol uptake/transporter homolog, GUP1, GUP1 glycerol uptake/transporter homolog, Hedgehog acyltransferase like, Hedgehog acyltransferase-like protein, Hhatl, HHATL_HUMAN, KIAA1173, MBOAT3, Membrane bound O acyltransferase domain containing 3, MSTP002, OACT3, Protein-cysteine N-palmitoyltransferase HHAT-like protein.

    Background: GUP1 is a 504 amino acid multipass membrane protein of the endoplasmic reticulum that functions as a membrane bound O-acyltransferase. With specific expression in heart, GUP1 negatively regulates amino-terminal palmitoylation of Shh by HHAT, a protein that is required for Shh signaling. Deletion of the gene encoding GUP1 results in higher sensibility to specific sphinogolipid biosynthesis inhibitors and resistance to ergosterol biosynthesis inhibitors, indicating that GUP1 is an essential component in lipid metabolism. Also, GUP1 also seems to be important for cell wall assembly and stability due to evidence in Saccharomyces cerevisiae GUP1 mutants, which exhibit altered plasma membrane lipid composition and membrane potential.

    基因ID

    57467

    途径

    Hedgehog Signaling
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