ALKBH1 抗体 (AA 1-100) (Cy5)
Quick Overview for ALKBH1 抗体 (AA 1-100) (Cy5) (ABIN1704770)
抗原
See all ALKBH1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-100
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交叉反应
- 小鼠, 大鼠
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预测反应
- Human,Dog,Cow,Sheep,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human ABH1/ALKB
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亚型
- IgG
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anti-AlkB, Alkylation Repair Homolog 1 (ALKBH1) antibody
ALKBH1 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-AlkB, Alkylation Repair Homolog 1 (ALKBH1) (AA 1-389) antibodyALKBH1 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-AlkB, Alkylation Repair Homolog 1 (ALKBH1) (AA 110-389) antibodyALKBH1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-AlkB, Alkylation Repair Homolog 1 (ALKBH1) (AA 1-389) antibodyALKBH1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-AlkB, Alkylation Repair Homolog 1 (ALKBH1) (AA 110-389) antibodyALKBH1 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-AlkB, Alkylation Repair Homolog 1 (ALKBH1) (AA 110-389) antibodyALKBH1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-AlkB, Alkylation Repair Homolog 1 (ALKBH1) antibodyALKBH1 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-AlkB, Alkylation Repair Homolog 1 (ALKBH1) (AA 97-146) antibodyALKBH1 适用: 人, 小鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-AlkB, Alkylation Repair Homolog 1 (ALKBH1) (Center) antibodyALKBH1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-AlkB, Alkylation Repair Homolog 1 (ALKBH1) (N-Term) antibodyALKBH1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- ALKBH1 (AlkB, Alkylation Repair Homolog 1 (ALKBH1))
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别名
- ABH1/ALKB
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背景
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Synonyms: ABH, ABH1, alkB, AlkB, alkylation repair homolog 1 E. coli, ALKB1_HUMAN, ALKBH, ALKBH1, Alkylated DNA repair protein alkB homolog 1, Alkylation repair homolog 1, Alkylation repair, alkB homolog, Alpha-ketoglutarate-dependent dioxygenase ABH1, DNA lyase ABH1, hABH.
Background: ALKB protects DNA and RNA against damage from methylating compounds from the environment by directly reversing 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) cytotoxic alkylation lesions in DNA and RNA. The enzymes act by oxidative demethylation, utilizing ferrous iron and alpha-ketoglutarate as cofactors, 2-oxoglutarate as a co-substrate, and molecular oxygen as the oxidizing agent. Deficiencies in DNA and RNA repair in mammals are associated with cancer, neurological disease and developmental defects. ALKB plays a role in resistance to anti-cancer drugs which attempt to damage tumor DNA. Escherichia coli ALKB protein belongs to the superfamily of 2-oxoglutarate- and iron(II)-dependent oxygenases.
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基因ID
- 8846
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途径
- DNA Damage Repair
抗原
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