NAE1 抗体 (AA 401-500) (Cy5)
Quick Overview for NAE1 抗体 (AA 401-500) (Cy5) (ABIN1704713)
抗原
See all NAE1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 401-500
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交叉反应
- 小鼠, 大鼠
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预测反应
- Human,Dog,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human APPBP1
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亚型
- IgG
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anti-NEDD8 Activating Enzyme E1 Subunit 1 (NAE1) (AA 229-534) antibody
NAE1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-NEDD8 Activating Enzyme E1 Subunit 1 (NAE1) (AA 1-534) antibodyNAE1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4E8-H3 unconjugated
anti-NEDD8 Activating Enzyme E1 Subunit 1 (NAE1) (AA 1-220), (Regulatory Subunit) antibodyNAE1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-NEDD8 Activating Enzyme E1 Subunit 1 (NAE1) (AA 1-534) antibodyNAE1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-NEDD8 Activating Enzyme E1 Subunit 1 (NAE1) (AA 1-534) antibodyNAE1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-NEDD8 Activating Enzyme E1 Subunit 1 (NAE1) (AA 430-459), (C-Term) antibodyNAE1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB8977 unconjugated
anti-NEDD8 Activating Enzyme E1 Subunit 1 (NAE1) (C-Term) antibodyNAE1 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-NEDD8 Activating Enzyme E1 Subunit 1 (NAE1) antibodyNAE1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-NEDD8 Activating Enzyme E1 Subunit 1 (NAE1) antibodyNAE1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-NEDD8 Activating Enzyme E1 Subunit 1 (NAE1) (AA 308-357) antibodyNAE1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- NAE1 (NEDD8 Activating Enzyme E1 Subunit 1 (NAE1))
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别名
- APPBP1
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背景
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Synonyms: HPP1, ula-1, APPBP1, A-116A10.1, NEDD8-activating enzyme E1 regulatory subunit, Amyloid beta precursor protein-binding protein 1, 59 kDa, APP-BP1, Amyloid protein-binding protein 1, Proto-oncogene protein 1, NAE1
Background: Regulatory subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Necessary for cell cycle progression through the S-M checkpoint. Overexpression of NAE1 causes apoptosis through deregulation of NEDD8 conjugation.
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基因ID
- 8883
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UniProt
- Q13564
抗原
-
