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VAV3 抗体 (pTyr141) (Cy5)

VAV3 适用: 小鼠, 大鼠 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal Cy5
产品编号 ABIN1704532
发货至: 中国
  • 抗原 See all VAV3 抗体
    VAV3 (Vav 3 Oncogene (VAV3))
    抗原表位
    • 15
    • 14
    • 11
    • 6
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pTyr141
    适用
    • 47
    • 30
    • 22
    • 1
    小鼠, 大鼠
    宿主
    • 60
    • 1
    克隆类型
    • 61
    多克隆
    标记
    • 21
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    This VAV3 antibody is conjugated to Cy5
    应用范围
    • 33
    • 25
    • 25
    • 22
    • 9
    • 8
    • 7
    • 4
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    小鼠, 大鼠
    预测反应
    Human,Cow,Sheep,Horse
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic phosphopeptide derived from human VAV3 around the phosphorylation site of Tyr141
    亚型
    IgG
    Top Product
    Discover our top product VAV3 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    VAV3 (Vav 3 Oncogene (VAV3))
    别名
    VAV3 (VAV3 产品)
    别名
    RGD1565941 antibody, A530094I06Rik antibody, AA986410 antibody, Idd18.1 antibody, vav guanine nucleotide exchange factor 3 antibody, vav 3 guanine nucleotide exchange factor antibody, vav 3 oncogene antibody, VAV3 antibody, Vav3 antibody
    背景

    Synonyms: VAV3phospho Y141, Guanine nucleotide exchange factor VAV3, Protein vav 3, Protein vav3, VAV 3, Vav 3 guanine nucleotide exchange factor, VAV 3 oncogene, VAV 3 protein, VAV-3, Vav3, VAV3 oncogene, VAV3 protein, VAV3_HUMAN.

    Background: The Vav family of Rho guanine nucleotide exchange factors (GEFs) orchestrate signaling events following lymphocyte antigen receptor activation. Vav3, like Vav (also known as Vav1 or p95Vav), undergoes tyrosine phosphorylation downstream of T cell receptor cross-linkage, and subsequently interacts with 2 adaptor molecules, SLP76 and 3BP2. Following these events, however, the paths of Vav and Vav3 diverge, Vav affects IL-2 promotor activity, while Vav3 impacts gene transcription linked to serum response element (SRE). Furthermore, Vav3 expression follows a cell cycle-dependent pattern, with transient upregulation occuring during mitosis. Encforced Vav3 expression leads to the appearance of multinucleate cells, implicating a role for Vav3 in the control of cytokinesis.

    基因ID
    10451
    途径
    Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway
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