DMC1 抗体 (AA 251-340) (Cy5)
Quick Overview for DMC1 抗体 (AA 251-340) (Cy5) (ABIN1704423)
抗原
See all DMC1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 251-340
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预测反应
- Human,Mouse,Rat,Cow,Pig,Horse,Chicken
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human DMC1
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亚型
- IgG
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anti-DNA Meiotic Recombinase 1 (DMC1) (AA 237-339) antibody
DMC1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4A10 unconjugated
anti-DNA Meiotic Recombinase 1 (DMC1) (AA 5-153) antibodyDMC1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-DNA Meiotic Recombinase 1 (DMC1) antibodyDMC1 适用: 人, 小鼠, 大鼠, Cow WB, IHC, IF, StM 宿主: 小鼠 Monoclonal 2H12-4 unconjugated
anti-DNA Meiotic Recombinase 1 (DMC1) (Center) antibodyDMC1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-DNA Meiotic Recombinase 1 (DMC1) antibodyDMC1 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-DNA Meiotic Recombinase 1 (DMC1) (AA 237-339) antibodyDMC1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4E2 unconjugated
anti-DNA Meiotic Recombinase 1 (DMC1) (Internal Region) antibodyDMC1 适用: 人, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-DNA Meiotic Recombinase 1 (DMC1) (AA 1-260) antibodyDMC1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-DNA Meiotic Recombinase 1 (DMC1) (AA 1-30), (N-Term) antibodyDMC1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB23872 unconjugated
anti-DNA Meiotic Recombinase 1 (DMC1) (AA 1-30), (N-Term) antibodyDMC1 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- DMC1 (DNA Meiotic Recombinase 1 (DMC1))
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别名
- Dmc1
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背景
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Synonyms: disrupted meiotic cDNA 1 homolog, dJ199H16.1, DMC 1, DMC1 dosage suppressor of mck1 homolog, DMC1 dosage suppressor of mck1 homolog meiosis specic homologous recombination yeast, DMC1 homologue, DMC1H, HsLim15, LIM15, Meiotic recombination protein DMC1/LIM15 homolog, MGC150472, MGC150473, DMC1_HUMAN.
Background: DNA repair proteins are necessary for the maintenance of chromosome integrity and are involved in the elimination of premutagenic lesions from DNA. The DNA repair proteins Rad51 and Rad52 are key components of the double-strand-break repair (DSBR) pathway. Rad51 is essential for mitotic and meiotic recombination, and its mutation in yeast and mammalian cells results in chromosome loss. Overexpression of Rad52 confers resistance to ionizing radiation and induces homologous intrachromosomal recombination. Rad52 is thought to be involved in an early stage of Rad51-mediated recombination. Additional proteins involved in the pathway include Nibrin and Dmc1. Nibrin, which complexes with Mre11 and Rad50, is absent in Nijemegen breakage syndrome (NBS) patients. Dmc1 is specifically involved in meiotic recombination. An alternative spliced form of Dmc1, designated Dmc1-D, is deleted for a region between the two motifs involved in nucleotide binding. The alternatively spliced Dmc1-D transcript is detected in both male and female germ cells, indicating that the encoded protein may have a role in mammalian genetic recombination in meiosis.
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基因ID
- 11144
抗原
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