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FMR1 抗体 (pSer500) (Cy5)

This anti-FMR1 antibody is a 兔 多克隆 antibody detecting FMR1 in WB, IF (cc) 和 IF (p). Suitable for 人, 小鼠, 大鼠 和 斑马鱼.
产品编号 ABIN1704395
发货至: 中国

Quick Overview for FMR1 抗体 (pSer500) (Cy5) (ABIN1704395)

抗原

See all FMR1 抗体
FMR1 (Fragile X Mental Retardation 1 (FMR1))

适用

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人, 小鼠, 大鼠, 斑马鱼

宿主

  • 62
  • 19
  • 2

克隆类型

  • 55
  • 28
多克隆

标记

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This FMR1 antibody is conjugated to Cy5

应用范围

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  • 5
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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 8
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    • 5
    • 5
    • 2
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    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    pSer500

    交叉反应

    人, 小鼠, 大鼠, 斑马鱼

    预测反应

    Dog,Cow,Sheep,Pig,Chicken,Rabbit,Guinea Pig

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human FMRP around the phosphorylation site of Ser500

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    FMR1 (Fragile X Mental Retardation 1 (FMR1))

    别名

    FMRP

    背景

    Synonyms: POF, FMRP, POF1, FRAXA, Fragile X mental retardation protein 1, Protein FMR-1, FMR1

    Background: Translation repressor. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates translation repression (By similarity). RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs. Associated with polysomes. May play a role in the transport of mRNA from the nucleus to the cytoplasm. Binds strongly to poly(G), binds moderately to poly(U) but shows very little binding to poly(A) or poly(C).

    基因ID

    2332

    UniProt

    Q06787

    途径

    Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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