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Ataxin 1 抗体 (pSer775) (Cy5)

ATXN1 适用: 人, 小鼠, 大鼠 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal Cy5
产品编号 ABIN1704367
发货至: 中国
  • 抗原 See all Ataxin 1 (ATXN1) 抗体
    Ataxin 1 (ATXN1)
    抗原表位
    • 27
    • 18
    • 17
    • 12
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer775
    适用
    • 70
    • 60
    • 32
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 64
    • 47
    • 1
    克隆类型
    • 64
    • 48
    多克隆
    标记
    • 47
    • 8
    • 7
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Ataxin 1 antibody is conjugated to Cy5
    应用范围
    • 84
    • 44
    • 42
    • 35
    • 29
    • 22
    • 22
    • 22
    • 9
    • 6
    • 5
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    人, 小鼠, 大鼠
    预测反应
    Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic phosphopeptide derived from human Ataxin 1 around the phosphorylation site of Ser776
    亚型
    IgG
    Top Product
    Discover our top product ATXN1 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    Ataxin 1 (ATXN1)
    别名
    Ataxin 1 (ATXN1 产品)
    背景

    Synonyms: Ataxin 1 phospho S776,p-Ataxin 1 phospho S776, ATX1, ATXN1, SCA1, Ataxin 1, Ataxin-1, Ataxin1, Spinocerebellar ataxia type 1, ATX1_HUMAN.

    Background: Ataxin-1, also designated spinocerebellar ataxia type 1 protein (Sca-1), is differentially expressed and localizes to both the cytoplasm and the nucleus. Mutations in Ataxin-1 are associated with the onset of the autosomal dominant neurodegenerative disorder spinocerebellar ataxia type 1 (SCA-1), which is characterized by progressive neuronal loss in the cerebellum, muscle wasting and ataxia. In Purkinje cells, where SCA-1 is predominantly observed, Ataxin-1 has been shown to directly associate with the Purkinje-enriched leucine-rich acidic nuclear protein (LANP) and the nuclear matrix-associated protein promyelocytic leukemia protein PML. In SCA-1, Ataxin-1 is mutated to encode a polyglutamine protein that forms nuclear aggregates, which interact significantly more strongly with LANP and contribute to the pathogenesis of SCA-1.

    基因ID
    6310
    途径
    Synaptic Membrane
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