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Dynamin 1 抗体 (AA 551-680) (Cy5)

DNM1 适用: 人 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal Cy5
产品编号 ABIN1704211
发货至: 中国
  • 抗原 See all Dynamin 1 (DNM1) 抗体
    Dynamin 1 (DNM1)
    抗原表位
    • 31
    • 31
    • 14
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 551-680
    适用
    • 105
    • 49
    • 46
    • 9
    • 8
    • 7
    • 3
    • 2
    • 2
    • 2
    • 1
    宿主
    • 98
    • 9
    • 2
    克隆类型
    • 106
    • 4
    多克隆
    标记
    • 50
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    This Dynamin 1 antibody is conjugated to Cy5
    应用范围
    • 87
    • 38
    • 38
    • 37
    • 20
    • 14
    • 13
    • 6
    • 6
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    预测反应
    Human,Mouse,Rat,Dog,Sheep,Pig,Horse,Chicken
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Dynamin 1
    亚型
    IgG
    Top Product
    Discover our top product DNM1 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    Dynamin 1 (DNM1)
    别名
    Dynamin 1 (DNM1 产品)
    别名
    DNM antibody, Dnm antibody, AI838169 antibody, Ftfl antibody, mKIAA4093 antibody, dnm antibody, DNM1 antibody, Dnm1 antibody, dnm1 antibody, si:dkey-246l19.2 antibody, dynamin 1 antibody, dynamin-1 antibody, dynamin 1a antibody, DNM1 antibody, Dnm1 antibody, BACOIKO008_37 antibody, PTRG_07818 antibody, PTRG_08097 antibody, dnm1 antibody, LOC100168088 antibody, LOC100199205 antibody, dnm1a antibody
    背景

    Synonyms: B dynamin, D100, DNM 1, DNM, DNM1, DYN1_HUMAN, Dynamin, Dynamin-1, Dynamin1.

    Background: Dynamin I is a GTPase enzyme required for the retrieval of synaptic vesicles after exocytosis and functions in endocytosis by stimulating assembly of invaginating synaptic vesicles (1). Dynamin I is phosphorylated in nerve terminals exclusively in the cytosolic compartment and in vitro by protein kinase C (PKC) (25). The phosphorylation site in PKC-phosphorylated Dynamin I is a single site at Serine 795, which is located near a binding site for the SH3 domain of p85, the regulatory subunit of phosphatidylinositol 3-kinase (25). Dephosphorylation is required for synaptic vesicle retrieval, suggesting that phosphorylation affects the subcellular localization of Dynamin I (5). Mouse, rat and human Dynamin I are phosphorylated on serine residues, including Ser 778, by Cdk5, regulating PACSIN1 recruitment and enabling synaptic vesicle endocytosis.

    基因ID
    1759
    途径
    Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
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