Dynamin 1 抗体 (DNM1) (Cy5)

Details for Product anti-DNM1 Antibody No. ABIN1704211
抗原
  • DNM
  • Dnm
  • AI838169
  • Ftfl
  • mKIAA4093
  • dnm
  • DNM1
  • Dnm1
  • dnm1
  • si:dkey-246l19.2
  • dynamin 1
  • dynamin-1
  • dynamin 1a
  • DNM1
  • Dnm1
  • BACOIKO008_37
  • PTRG_07818
  • PTRG_08097
  • dnm1
  • LOC100168088
  • LOC100199205
  • dnm1a
适用
人, 小鼠, 大鼠
190
152
143
15
15
11
3
2
2
2
1
宿主

167
20
13
克隆类型
多克隆
标记
This Dynamin 1 antibody is conjugated to Cy5
8
7
7
7
7
7
6
4
4
3
3
3
3
3
1
应用范围
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
124
59
51
38
21
8
7
7
5
5
2
2
2
1
选项
免疫原 KLH conjugated synthetic peptide derived from human Dynamin 1
亚型 IgG
纯化方法 Purified by Protein A.
Plasmids, Primers & others Plasmids, Primers & others Dynamin 1 products on genomics-online (e.g. as negative or positive controls)
抗原
别名 Dynamin 1 (DNM1 Antibody 摘要)
背景

Dynamin I is a GTPase enzyme required for the retrieval of synaptic vesicles after exocytosis and functions in endocytosis by stimulating assembly of invaginating synaptic vesicles (1). Dynamin I is phosphorylated in nerve terminals exclusively in the cytosolic compartment and in vitro by protein kinase C (PKC) (2â€"5). The phosphorylation site in PKC-phosphorylated Dynamin I is a single site at Serine 795, which is located near a binding site for the SH3 domain of p85, the regulatory subunit of phosphatidylinositol 3-kinase (2â€"5). Dephosphorylation is required for synaptic vesicle retrieval, suggesting that phosphorylation affects the subcellular localization of Dynamin I (5). Mouse, rat and human Dynamin I are phosphorylated on serine residues, including Ser 778, by Cdk5, regulating PACSIN1 recruitment and enabling synaptic vesicle endocytosis.

Synonyms: B dynamin, D100, DNM 1, DNM, DNM1, DYN1_HUMAN, Dynamin, Dynamin-1, Dynamin1.

基因ID 1759
途径 Toll-Like Receptors Cascades, CXCR4-mediated Signaling Events, Thromboxane A2 Receptor Signaling
应用备注 IF(IHC-P) 1:50-200
限制 仅限研究用
状态 Liquid
浓度 1 μg/μL
缓冲液 Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
储存液 Sodium azide
注意事项 This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
储存条件 4 °C
储存方法 Store at 4°C
有效期 12 months
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