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EEF2K 抗体 (pSer359) (Cy5)

This anti-EEF2K antibody is a 兔 多克隆 antibody detecting EEF2K in WB, IF (p) 和 IF (cc). Suitable for 人.
产品编号 ABIN1704156
发货至: 中国

Quick Overview for EEF2K 抗体 (pSer359) (Cy5) (ABIN1704156)

抗原

See all EEF2K 抗体
EEF2K (Eukaryotic Elongation Factor-2 Kinase (EEF2K))

适用

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宿主

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克隆类型

  • 87
多克隆

标记

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This EEF2K antibody is conjugated to Cy5

应用范围

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Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
  • 抗原表位

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    pSer359

    预测反应

    Human,Mouse,Rat,Dog,Sheep,Horse,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human EEF2k around the phosphorylation site of Ser359

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    EEF2K (Eukaryotic Elongation Factor-2 Kinase (EEF2K))

    别名

    EEF2k

    背景

    Synonyms: EEF2K phospho S359, p-EEF2K phospho S359, Calcium/calmodulin dependent eukaryotic elongation factor 2, Calcium/calmodulin dependent eukaryotic elongation factor 2 kinase, Calmodulin dependent protein kinase III, cb365, eEF 2 kinase, eEF 2K, EEF2K protein, Elongation factor 2 kinase, Eukaryotic elongation factor 2 kinase, kinase eEF2K, SMEF2K, EF2K_HUMAN.

    Background: Eukaryotic elongation factor 2 kinase (EEF2k) previously known as Ca2+/calmodulin dependent protein kinase III, is an abundant cytoplasmic protein highly specific for elongation factor 2 (eEf2). Phosphorylation of eEF2 by eEF2 kinase on specific threonine residues results in the inactivation of eEF-2 and in termination of mRNA translation. The activity of eEF2 kinase is not only dependent upon Ca2+ ions, calmodulin (CaM) and insulin, but is also regulated both negatively and positively via phosphorylation by different protein kinases (AMPK, S6K1, p90 RSK). There is also evidence that eEF-2 phosphorylation is involved in the regulation of cell cycle progression, cellular differentiation, oogensis and malignant tumors.

    基因ID

    29904

    途径

    AMPK Signaling
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