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GAS41 抗体 (AA 151-227) (Cy5)

This anti-GAS41 antibody is a 兔 多克隆 antibody detecting GAS41 in WB, IF (cc) 和 IF (p). Suitable for 小鼠 和 非洲爪蟾.
产品编号 ABIN1704121
发货至: 中国

Quick Overview for GAS41 抗体 (AA 151-227) (Cy5) (ABIN1704121)

抗原

GAS41 (YEATS Domain Containing 4)

适用

  • 52
  • 41
  • 15
  • 14
  • 6
  • 6
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
小鼠, 非洲爪蟾

宿主

  • 56
  • 10

克隆类型

  • 58
  • 8
多克隆

标记

  • 29
  • 5
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This GAS41 antibody is conjugated to Cy5

应用范围

  • 50
  • 25
  • 12
  • 12
  • 5
  • 4
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 151-227

    交叉反应

    小鼠, 非洲爪蟾

    预测反应

    Human,Rat,Cow,Horse,Chicken,Rabbit,Zebrafish

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human GAS41

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    GAS41 (YEATS Domain Containing 4)

    别名

    GAS41

    背景

    Synonyms: 4930573H17Rik, B230215M10Rik, GAS 41, Gas41, glioma amplied sequence 41, Glioma-amplied sequence 41, glioma-amplied sequence-41, gliomaamplied sequence 41, gliomaamplied sequence41, NUBI 1, NuBI-1, NuBI1, NuMA binding protein 1, NuMA-binding protein 1, YAF9, YEATS domain containing 4, YEATS domain containing4, YEATS domain-containing protein 4, YEATS4, YETS4_HUMAN.

    Background: Gene amplification is associated with tumor stage and progression in human gliomas. Several amplified loci are identified and comprise multiple genes. The glioma amplified sequence 41 (GAS41) is an evolutionarily conserved eukaryotic protein found in diverse species. GAS41 is related to the AF-9 and ENL proteins, which are putative transcription factors in some acute leukemias, and interacts with a component of the nuclear matrix, NuMA, in interphase cells. GAS41 has a dotted staining pattern in interphase nuclei and a uniform distribution in mitotic cells. GAS41 is ubiquitously expressed, with the highest levels of expression in human brain. In neuroblastoma, GAS41 is located in the nucleoli, but not in the nucleoplasm. GAS41 also binds to the MLL fusion partner AF10, which is involved in two distinct chromosomal translocations associated with hematologic malignancy. In addition, GAS41 interacts with INI1 (Integrase Interactor), which is a human homologue of the yeast SNF5 protein, a component of the SWI/SNF complex. The GAS41 gene maps to human chromosome 12q13-q15.

    基因ID

    8089
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