WISP3 抗体 (AA 221-320) (Cy3)
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北京 101111
Quick Overview for WISP3 抗体 (AA 221-320) (Cy3) (ABIN1702793)
抗原
See all WISP3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 221-320
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交叉反应
- 大鼠
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预测反应
- Human,Mouse,Dog,Sheep,Horse,Rabbit,Monkey
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human WISP3
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亚型
- IgG
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anti-Wnt1 Inducible Signaling Pathway Protein 3 (WISP3) (AA 201-372) antibody
WISP3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Wnt1 Inducible Signaling Pathway Protein 3 (WISP3) antibodyWISP3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Wnt1 Inducible Signaling Pathway Protein 3 (WISP3) (AA 305-335) antibodyWISP3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB2145-2146 unconjugated
anti-Wnt1 Inducible Signaling Pathway Protein 3 (WISP3) antibodyWISP3 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Wnt1 Inducible Signaling Pathway Protein 3 (WISP3) (AA 42-260) antibodyWISP3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Wnt1 Inducible Signaling Pathway Protein 3 (WISP3) (AA 1-372) antibodyWISP3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Wnt1 Inducible Signaling Pathway Protein 3 (WISP3) (N-Term) antibodyWISP3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Wnt1 Inducible Signaling Pathway Protein 3 (WISP3) (Middle Region) antibodyWISP3 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- WISP3 (Wnt1 Inducible Signaling Pathway Protein 3 (WISP3))
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别名
- WISP3
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背景
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Synonyms: CCN 6, CCN family member 6, CCN6, CYR61, LIBC, Lost in inflammatory breast cancer tumor suppressor protein, MGC125987, MGC125988, MGC125989, OTTHUMP00000040421, PPAC, PPD, UNQ462/PRO790/PRO956, WISP 3, WISP-3, WISP3, WISP3_HUMAN, WNT 1 inducible signaling pathway protein 3, Wnt 1 signaling pathway protein 3, WNT1 inducible signaling pathway protein 3, WNT1 inducible signaling pathway protein 3 precursor, WNT1-inducible-signaling pathway protein 3.
Background: Wnt-induced secreted protein (WISP)-1, WISP-2 and WISP-3 are members of the CCN family of growth factors, which include connective tissue growth factor (CTGF) and Cyr61. WISP-1, WISP-2 and WISP-3 share significant sequence similarity, including four conserved cysteine-rich domains, and they are believed to function as dimers in their active forms. WISP-1 expression is observed in various tissues including adult heart, kidney and spleen, while WISP-2 expression predominates in skeletal muscle, colon and ovary. Both WISP-1 and WISP-2 are upregulated in cells transformed with the proto-oncogene Wnt-1, and they are also more highly expressed in human colon tumors, suggesting that these proteins may participate in tumor development. WISP-3 is involved in normal post-natal skeletal growth, and it is also implicated in the development of the autosomal recessive skeletal disorder progressive pseudorheumatoid dysplasia, which affects cartilage homeostasis by disrupting the growth of chondrocyte and normal cell columnar organization.
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基因ID
- 8838
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途径
- WNT signaling, Growth Factor Binding
抗原
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