DTX2 抗体 (AA 331-430) (Cy3)
Quick Overview for DTX2 抗体 (AA 331-430) (Cy3) (ABIN1702080)
抗原
See all DTX2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 331-430
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预测反应
- Human,Mouse,Rat,Horse,Zebrafish
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human DTX2
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亚型
- IgG
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anti-Deltex Homolog 2 (DTX2) (AA 1-622) antibody
DTX2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Deltex Homolog 2 (DTX2) (AA 1-280) antibodyDTX2 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Deltex Homolog 2 (DTX2) (AA 1-280) antibodyDTX2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Deltex Homolog 2 (DTX2) (AA 454-503) antibodyDTX2 适用: 人, 小鼠, 大鼠, 犬, Cow, 山羊, 豚鼠, 马, 兔, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Deltex Homolog 2 (DTX2) (AA 1-622) antibodyDTX2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Deltex Homolog 2 (DTX2) (Internal Region) antibodyVerified DTX2 适用: 人 IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Deltex Homolog 2 (DTX2) antibodyDTX2 适用: 人, 犬, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- DTX2 (Deltex Homolog 2 (DTX2))
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别名
- DTX2
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背景
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Synonyms: Deltex 2, Deltex2, hDTX2, Highly similar to hPMSR6 [H.sapiens], Protein deltex 2, RING finger protein 58, RNF58, Zinc ion binding protein, DTX2_HUMAN.
Background: DTX2 belongs to the Deltex family. It contains one RING-type zinc finger and two WWE domains. DTX2 is a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. It probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context, mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. DTX2 also functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity. The WWE domains are thought to mediate some protein-protein interaction, and are frequently found in ubiquitin ligases. There are two named isoforms.
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基因ID
- 113878
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途径
- Notch Signaling
抗原
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