VAV3 抗体 (pTyr141) (Biotin)
Quick Overview for VAV3 抗体 (pTyr141) (Biotin) (ABIN1700908)
抗原
See all VAV3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pTyr141
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交叉反应
- 小鼠, 大鼠
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预测反应
- Human,Cow,Sheep,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic phosphopeptide derived from human VAV3 around the phosphorylation site of Tyr141
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亚型
- IgG
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anti-Vav 3 Oncogene (VAV3) (AA 183-380) antibody
VAV3 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Vav 3 Oncogene (VAV3) (Internal Region) antibodyVerified VAV3 适用: 人 ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Vav 3 Oncogene (VAV3) (AA 701-800) antibodyVAV3 适用: 人, 大鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Vav 3 Oncogene (VAV3) (AA 560-680) antibodyVAV3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Vav 3 Oncogene (VAV3) (AA 398-583) antibodyVAV3 适用: 人 WB, ELISA, IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Vav 3 Oncogene (VAV3) (AA 562-674) antibodyVAV3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Vav 3 Oncogene (VAV3) antibodyVAV3 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Vav 3 Oncogene (VAV3) (pTyr173) antibodyVAV3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Vav 3 Oncogene (VAV3) (pTyr173) antibodyVAV3 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Vav 3 Oncogene (VAV3) (AA 768-802), (C-Term) antibodyVAV3 适用: 人 WB 宿主: 兔 Polyclonal RB53259 unconjugated
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应用备注
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C for 12 months.
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有效期
- 12 months
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- VAV3 (Vav 3 Oncogene (VAV3))
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别名
- VAV3
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背景
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Synonyms: VAV3phospho Y141, Guanine nucleotide exchange factor VAV3, Protein vav 3, Protein vav3, VAV 3, Vav 3 guanine nucleotide exchange factor, VAV 3 oncogene, VAV 3 protein, VAV-3, Vav3, VAV3 oncogene, VAV3 protein, VAV3_HUMAN.
Background: The Vav family of Rho guanine nucleotide exchange factors (GEFs) orchestrate signaling events following lymphocyte antigen receptor activation. Vav3, like Vav (also known as Vav1 or p95Vav), undergoes tyrosine phosphorylation downstream of T cell receptor cross-linkage, and subsequently interacts with 2 adaptor molecules, SLP76 and 3BP2. Following these events, however, the paths of Vav and Vav3 diverge, Vav affects IL-2 promotor activity, while Vav3 impacts gene transcription linked to serum response element (SRE). Furthermore, Vav3 expression follows a cell cycle-dependent pattern, with transient upregulation occuring during mitosis. Encforced Vav3 expression leads to the appearance of multinucleate cells, implicating a role for Vav3 in the control of cytokinesis.
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基因ID
- 10451
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途径
- Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway
抗原
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