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TSC1 抗体 (AA 701-800) (Biotin)

This anti-TSC1 antibody is a 兔 多克隆 antibody detecting TSC1 in ELISA, WB, IHC (p) 和 IHC (fro). Suitable for 人.
产品编号 ABIN1700334
发货至: 中国

Quick Overview for TSC1 抗体 (AA 701-800) (Biotin) (ABIN1700334)

抗原

See all TSC1 抗体
TSC1 (Tuberous Sclerosis 1 (TSC1))

适用

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宿主

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克隆类型

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多克隆

标记

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This TSC1 antibody is conjugated to Biotin

应用范围

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ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
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    AA 701-800

    预测反应

    Human,Mouse,Rat

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Hamartin

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    TSC1 (Tuberous Sclerosis 1 (TSC1))

    别名

    Hamartin

    背景

    Synonyms: Hamartin, kiaa0243, LAM, TSC, TSC1, Tsc1 gene, TSC1_HUMAN, Tuberous sclerosis 1, Tuberous sclerosis 1 protein.

    Background: Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disorder characterized by mental retardation and the widespread development of distinctive tumors termed hamartomas. Two different genetic loci have been linked to TSC, one of these loci, the tuberous sclerosis-2 gene (TSC2), encodes a protein called tuberin and the other loci, tuberous sclerosis-1 gene (TSC1), encodes a protein called hamartin. Tuberin and hamartin interact with each other forming a cystoplasmic complex. Hamartin interacts with the ezrin-radixin-moesin (ERM) family of actin-binding proteins and inhibition of hamartin activity results in loss of cell adhesion. Hamartin is present in most adult tissues with strong expression in brain, heart, and kidney.

    基因ID

    7248

    途径

    RTK signaling, AMPK Signaling, Regulation of Cell Size, Tube Formation
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