Chloride Channel 5 抗体 (AA 1-100) (Biotin)
Quick Overview for Chloride Channel 5 抗体 (AA 1-100) (Biotin) (ABIN1700244)
抗原
See all Chloride Channel 5 (CLCN5) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 1-100
-
预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human Chloride Channel 5/CLC5
-
亚型
- IgG
-
-
anti-Chloride Channel 5 (CLCN5) (Middle Region) antibody
CLCN5 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 绵羊, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-Chloride Channel 5 (CLCN5) antibodyCLCN5 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Chloride Channel 5 (CLCN5) (AA 15-41), (N-Term) antibodyCLCN5 适用: 人 WB 宿主: 兔 Polyclonal RB42009 unconjugated
anti-Chloride Channel 5 (CLCN5) (Internal Region) antibodyCLCN5 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chloride Channel 5 (CLCN5) (AA 553-746) antibodyCLCN5 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Chloride Channel 5 (CLCN5) (AA 566-665) antibodyCLCN5 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Chloride Channel 5 (CLCN5) (AA 521-570) antibodyCLCN5 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 绵羊 WB 宿主: 兔 Polyclonal unconjugated
anti-Chloride Channel 5 (CLCN5) (AA 637-816) antibodyCLCN5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
IHC-P 1:200-400
IHC-F 1:100-500 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C for 12 months.
-
有效期
- 12 months
-
-
- Chloride Channel 5 (CLCN5)
-
别名
- Chloride Channel 5
-
背景
-
Synonyms: Chloride channel protein 5, Chloride transporter ClC-5, ClC-5, CLC5, CLCK2, CLCN5, CLCN5_HUMAN, DENTS, H+/Cl- exchange transporter 5, hCIC-K2, NPHL1, NPHL2, XLRH, XRN.
Background: The family of voltage-dependent chloride channels (CLCs) regulate cellular trafficking of chloride ions, a critical component of all living cells. CLCs regulate excitability in muscle and nerve cells, aid in organic solute transport and maintain cellular volume. The genes encoding human CLC-1 through CLC-7 map to chromosomes 7q32, 3q28, 4q32, Xp22.3, Xp11.23-p11.22, 1p36 and 16p13, respectively. CLC1 is highly expressed in skeletal muscle. Mutations in the gene encoding CLC1 lead to myotonia, an inheritable disorder characterized by muscle stiffness and renal salt wasting. CLC2 is highly expressed in the epithelia of several organs including lung, which suggests CLC2 may be a possible therapeutic target for cystic fibrosis. CLC3 expression is particularly abundant in neuronal tissue, while CLC4 expression is evident in skeletal and cardiac muscle as well as brain. Mutations in the gene encoding CLC5 lead to Dent?s disease, a renal disorder characterized by proteinuria and hypercalciuria. CLC6 and CLC7 are broadly expressed in several tissues including testis, kidney, brain and muscle.
抗原
-
