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Androgen Receptor 抗体 (pSer94) (Biotin)

This anti-Androgen Receptor antibody is a 兔 多克隆 antibody detecting Androgen Receptor in IHC (p) 和 IHC (fro). Suitable for 人.
产品编号 ABIN1700095
发货至: 中国

Quick Overview for Androgen Receptor 抗体 (pSer94) (Biotin) (ABIN1700095)

抗原

See all Androgen Receptor (AR) 抗体
Androgen Receptor (AR)

适用

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克隆类型

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多克隆

标记

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This Androgen Receptor antibody is conjugated to Biotin

应用范围

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Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
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    pSer94

    交叉反应

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human Androgen Receptor around the phosphorylation site of Ser94

    亚型

    IgG
  • 应用备注

    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    Androgen Receptor (AR)

    别名

    Androgen Receptor

    背景

    Synonyms: Androgen Receptor phospho S94, Androgen Receptor Ser94, Androgen Receptor phospho Ser94, p-Androgen Receptor Ser94, ANDR_HUMAN, HYSP1, AIS, Androgen receptor dihydrotestosterone receptor, testicular feminization, spinal and bulbar muscular atrophy, Kennedy disease, AR, DHTR, Dihydro Testosterone Receptor, Dihydrotestosterone receptor, HUMARA, Nuclear receptor subfamily 3 group C member 4, SBMA, SMAX1, Spinal and bulbar muscular atrophy, TFM.

    Background: The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

    基因ID

    367

    途径

    Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Nuclear Hormone Receptor Binding, Chromatin Binding
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