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LIMD1 抗体 (AA 21-120) (AbBy Fluor® 647)

This anti-LIMD1 antibody (ABIN1699002) is a Rabbit Polyclonal antibody detecting LIMD1 in IF (cc), IF (p). Suitable for Mouse.
产品编号 ABIN1699002
发货至: 中国

Quick Overview for LIMD1 抗体 (AA 21-120) (AbBy Fluor® 647) (ABIN1699002)

抗原

See all LIMD1 抗体
LIMD1 (LIM Domains Containing 1 (LIMD1))

适用

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小鼠

宿主

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克隆类型

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多克隆

标记

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This LIMD1 antibody is conjugated to AbBy Fluor® 647

应用范围

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Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
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    AA 21-120

    交叉反应

    小鼠

    预测反应

    Human,Rat,Cow,Sheep,Pig,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Limd1

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    LIMD1 (LIM Domains Containing 1 (LIMD1))

    别名

    Limd1

    背景

    Synonyms: AW822033, D9Ertd192e, LIM domain-containing protein 1, LIM domains containing 1, LIMD1, LIMD1_HUMAN, OTTHUMP00000164657, OTTHUMP00000210317, rCG_25194.

    Background: The Zyxin family of proteins contains five members: Ajuba, Limd1, LPP, TRIP6 and Zyxin. Limd1 (LIM domain-containing protein 1) is a ubiquitously expressed tumor suppressor containing 3 LIM zinc-binding domains. LIM domains consist of a cysteine-rich consensus sequence containing two distinct zinc-binding subdomains, which mediate protein-protein interactions. Limd1 interacts with the proteins SQSTM1, Rb, p62 and TRAF6. Limd1 was first identified when the deletion of its gene was noted in some cervical cancers. Limd1 blocks in vitro and in vivo tumor growth and is down-regulated in lung cancer. Limd1 may regulate osteoclast development under stressful conditions via its interactions with TRAF6 and p62.

    基因ID

    8994

    途径

    Ribonucleoprotein Complex Subunit Organization
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