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LIMD1 抗体 (AA 1-200)

LIMD1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7268259
发货至: 中国
  • 抗原 See all LIMD1 抗体
    LIMD1 (LIM Domains Containing 1 (LIMD1))
    抗原表位
    • 15
    • 8
    • 8
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 1-200
    适用
    • 33
    • 19
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 39
    • 2
    克隆类型
    • 39
    • 2
    多克隆
    标记
    • 17
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This LIMD1 antibody is un-conjugated
    应用范围
    • 23
    • 19
    • 17
    • 13
    • 13
    • 8
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    原理
    LIMD1 Rabbit pAb
    序列
    MDKYDDLGLE ASKFIEDLNM YEASKDGLFR VDKGAGNNPE FEETRRVFAT KMAKIHLQQQ QQQLLQEETL PRGSRGPVNG GGRLGPQARW EVVGSKLTVD GAAKPPLAAS TGAPGAVTTL AAGQPPYPPQ EQRSRPYLHG TRHGSQDCGS RESLATSEMS AFHQPGPCED PSCLTHGDYY DNLSLASPKW GDKPGVSPSI
    交叉反应
    人, 小鼠
    产品特性
    Polyclonal Antibodies
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human LIMD1 (NP_055055.1).
    亚型
    IgG
    Top Product
    Discover our top product LIMD1 Primary Antibody
  • 应用备注
    WB,1:500 - 1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    LIMD1 (LIM Domains Containing 1 (LIMD1))
    别名
    LIMD1 (LIMD1 产品)
    别名
    AW822033 antibody, D9Ertd192e antibody, xlimd1 antibody, LIM domains containing 1 antibody, LIM domains containing 1 L homeolog antibody, LIMD1 antibody, Limd1 antibody, limd1 antibody, limd1.L antibody
    背景
    Adapter or scaffold protein which participates in the assembly of numerous protein complexes and is involved in several cellular processes such as cell fate determination, cytoskeletal organization, repression of gene transcription, cell-cell adhesion, cell differentiation, proliferation and migration. Positively regulates microRNA (miRNA-mediated gene silencing and is essential for P-body formation and integrity. Acts as a hypoxic regulator by bridging an association between the prolyl hydroxylases and VHL enabling efficient degradation of HIF1A. Acts as a transcriptional corepressor for SNAI1- and SNAI2/SLUG-dependent repression of E-cadherin transcription. Negatively regulates the Hippo signaling pathway and antagonizes phosphorylation of YAP1. Inhibits E2F-mediated transcription, and suppresses the expression of the majority of genes with E2F1-responsive elements. Regulates osteoblast development, function, differentiation and stress osteoclastogenesis. Enhances the ability of TRAF6 to activate adapter protein complex 1 (AP-1 and negatively regulates the canonical Wnt receptor signaling pathway in osteoblasts. May act as a tumor suppressor by inhibiting cell proliferation.,LIMD1,Epigenetics & Nuclear Signaling,LIMD1
    基因ID
    8994
    UniProt
    Q9UGP4
    途径
    Ribonucleoprotein Complex Subunit Organization
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