电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

DTX2 抗体 (AA 331-430) (AbBy Fluor® 647)

This anti-DTX2 antibody is a 兔 多克隆 antibody detecting DTX2 in WB, IF (cc) 和 IF (p). Suitable for 人.
产品编号 ABIN1698454
发货至: 中国

Quick Overview for DTX2 抗体 (AA 331-430) (AbBy Fluor® 647) (ABIN1698454)

抗原

See all DTX2 抗体
DTX2 (Deltex Homolog 2 (DTX2))

适用

  • 34
  • 5
  • 5
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1

宿主

  • 31
  • 2
  • 1

克隆类型

  • 34
多克隆

标记

  • 15
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This DTX2 antibody is conjugated to AbBy Fluor® 647

应用范围

  • 26
  • 12
  • 12
  • 8
  • 4
  • 3
  • 3
  • 1
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 331-430

    预测反应

    Human,Mouse,Rat,Horse,Zebrafish

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human DTX2

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    DTX2 (Deltex Homolog 2 (DTX2))

    别名

    DTX2

    背景

    Synonyms: Deltex 2, Deltex2, hDTX2, Highly similar to hPMSR6 [H.sapiens], Protein deltex 2, RING finger protein 58, RNF58, Zinc ion binding protein, DTX2_HUMAN.

    Background: DTX2 belongs to the Deltex family. It contains one RING-type zinc finger and two WWE domains. DTX2 is a regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. It probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context, mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. DTX2 also functions as an ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity. The WWE domains are thought to mediate some protein-protein interaction, and are frequently found in ubiquitin ligases. There are two named isoforms.

    基因ID

    113878

    途径

    Notch Signaling
You are here:
Chat with us!