CYP11B2 抗体 (AA 251-350) (AbBy Fluor® 647)
Quick Overview for CYP11B2 抗体 (AA 251-350) (AbBy Fluor® 647) (ABIN1698442)
抗原
See all CYP11B2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 251-350
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交叉反应
- 人
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预测反应
- Mouse,Rat,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human CYP11B2
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- CYP11B2 (Cytochrome P450, Family 11, Subfamily B, Polypeptide 2 (CYP11B2))
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别名
- CYP11B2
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背景
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Synonyms: CYP 11B2, CYP11B2, CYPXI11B2, Cytochrome P450 1111B2, Cytochrome P450 1111B2 mitochondrial, Cytochrome P450 family 11 subfamily B polypeptide 2, Cytochrome P450 subfamily XIB cholesterol side chain cleavage, Cytochrome P450 subfamily XI11B2, Cytochrome P450C1111B2, C11B2_HUMAN.
Background: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane. The enzyme has steroid 18-hydroxylase activity to synthesize aldosterone and 18-oxocortisol as well as steroid 11 beta-hydroxylase activity. Mutations in this gene cause corticosterone methyl oxidase deficiency. [provided by RefSeq, Jul 2008].
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途径
- ACE Inhibitor Pathway, Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Systemic Arterial Blood Pressure by Hormones, C21-Steroid Hormone Metabolic Process, Feeding Behaviour
抗原
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