Sp3 抗体 (AA 651-750) (AbBy Fluor® 555)
Quick Overview for Sp3 抗体 (AA 651-750) (AbBy Fluor® 555) (ABIN1696884)
抗原
See all Sp3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 651-750
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预测反应
- Human,Mouse,Rat,Cow,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human SP3
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- Sp3 (Sp3 Transcription Factor (Sp3))
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别名
- SP3
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背景
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Synonyms: D130027J01Rik, DKFZp686O1631, GC binding transcription factor Sp 3, GC binding transcription factor Sp3, MGC105187, OTTMUSP00000014207, SP 3, Sp 3 transcription factor, SP3, Sp3 transcription factor, SP3_HUMAN, Specicity protein 3, SPR 2, SPR-2, SPR2, Transcription factor SP 3, Transcription factor SP3, Transcription factor Sp3.
Background: The Sp transcription factor family includes Sp1, Sp2, Sp3 (SPR-2) and Sp4 (SPR-1). Sp transcription factors share similar structures but do not share simi-lar functions. All four proteins contain a highly conserved DNA-binding domain composed of three zinc fingers at the C-terminus. Sp family members bind the consensus sequence GGGGCGGGGC and other closely related sequences which are known as GC boxes. Sp1, Sp3 and Sp4 share a high affinity for GC boxes while Sp2 does not. Sp2 only weakly binds to GT boxes. Sp1, Sp2 and Sp3 are ubiquitously expressed, while Sp4 is abundantly expressed in brain with limited expression in other tissues. Sp1 and Sp3, but not Sp2 or Sp4, interact with E2, a regulatory element for the 4 subunit of neuronal nicotinic acetylcholine receptors. Sp3 is the only Sp member to inhibit Sp1 and Sp4 media
抗原
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