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Glutaredoxin 2 抗体 (AA 101-164) (AbBy Fluor® 350)

This AbBy Fluor® 350-conjugated 兔 多克隆 anti-Glutaredoxin 2 antibody specifically detects Glutaredoxin 2 in WB, FACS, IF (cc) 和 IF (p). The antibody is reactive with 人 和 大鼠 samples.
产品编号 ABIN1693781
发货至: 中国
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Quick Overview for Glutaredoxin 2 抗体 (AA 101-164) (AbBy Fluor® 350) (ABIN1693781)

抗原

See all Glutaredoxin 2 (GRX2) 抗体
Glutaredoxin 2 (GRX2)

适用

  • 47
  • 21
  • 8
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
人, 大鼠

宿主

  • 41
  • 6

克隆类型

  • 45
  • 2
多克隆

标记

  • 22
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Glutaredoxin 2 antibody is conjugated to AbBy Fluor® 350

应用范围

  • 33
  • 21
  • 12
  • 12
  • 11
  • 9
  • 7
  • 7
  • 6
  • 3
  • 3
  • 2
Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 15
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 101-164

    交叉反应

    人, 大鼠

    预测反应

    Mouse,Dog,Cow,Sheep,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Glutaredoxin 2

    亚型

    IgG
  • 应用备注

    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    Glutaredoxin 2 (GRX2)

    别名

    Glutaredoxin 2

    背景

    Synonyms: GRX2, CGI-133, Glutaredoxin-2, mitochondrial, GLRX2

    Background: Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides. Can receive electrons not only from glutathione (GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Overexpression decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release.

    基因ID

    51022

    UniProt

    Q9NS18

    途径

    Cell RedoxHomeostasis
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