Inversin 抗体 (AA 31-130) (AbBy Fluor® 350)
Our Local Distributor
北京 101111
Quick Overview for Inversin 抗体 (AA 31-130) (AbBy Fluor® 350) (ABIN1693617)
抗原
See all Inversin (INVS) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 31-130
-
交叉反应
- 人, 小鼠
-
预测反应
- Rat,Cow,Sheep,Chimpanzee
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human Inversin
-
亚型
- IgG
-
-
anti-Inversin (INVS) (AA 1-101) antibody
INVS 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Inversin (INVS) (AA 1-237) antibodyINVS 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Inversin (INVS) (AA 1-91) antibodyINVS 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Inversin (INVS) (AA 1-90) antibodyINVS 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
有效期
- 12 months
-
-
- Inversin (INVS)
-
别名
- Inversin
-
背景
-
Synonyms: INV, Inversion of embryo turning homolog, inversion of embryonic turning, INVS, Nephrocystin 2, Nephrocystin-2, Nephrocystin2, nephronophthisis 2 infantile, NPH2, NPHP2, INVS_HUMAN.
Background: Nephrocystin-2 is a 1,065 amino acid protein that exists as three alternatively spliced isoforms and is essential for establishment of the left-right axis and normal renal development. Localizing to the cytoplasm, cytoskeleton, membrane and nucleus, nephrocystin-2 is expressed during presomite-stage embryos and persists in adulthood, with high levels of expression in liver and kidney. Mice expressing nephrocystin-2 mutations are primarily generated by random insertional mutagenesis and result in the reversal of left/right polarity and cyst formation in the kidneys. Furthermore, altered nephrocystin-2 function reverses nodal and lefty expression, indicating that nephrocystin-2 signaling occurs upstream of these proteins involved in the development of asymmetry.
-
基因ID
- 27130
抗原
-
