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c-FOS 抗体 (pSer362) (AbBy Fluor® 350)

This anti-c-FOS antibody is a 兔 多克隆 antibody detecting c-FOS in WB, IF (cc) 和 IF (p). Suitable for 人, 大鼠 和 小鼠.
产品编号 ABIN1693477
发货至: 中国

Quick Overview for c-FOS 抗体 (pSer362) (AbBy Fluor® 350) (ABIN1693477)

抗原

See all c-FOS (c-Fos) 抗体
c-FOS (c-Fos) (c-Fos)

适用

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人, 大鼠, 小鼠

宿主

  • 186
  • 22
  • 6
  • 1
  • 1

克隆类型

  • 189
  • 24
  • 1
多克隆

标记

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  • 9
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This c-FOS antibody is conjugated to AbBy Fluor® 350

应用范围

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  • 25
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  • 9
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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

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    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    pSer362

    交叉反应

    人, 小鼠, 大鼠

    预测反应

    Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human c-Fos around the phosphorylation site of Ser362

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    c-FOS (c-Fos) (c-Fos)

    别名

    c-Fos

    背景

    Synonyms: p55, AP-1, C-FOS, Proto-oncogene c-Fos, Cellular oncogene fos, G/G1 switch regulatory protein 7, FOS, GS7

    Background: Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. In the heterodimer, FOS and JUN/AP-1 basic regions each seems to interact with symmetrical DNA half sites. On TGF-beta activation, forms a multimeric SMAD3/SMAD4/JUN/FOS complex at the AP1/SMAD-binding site to regulate TGF-beta-mediated signaling. Has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation. In growing cells, activates phospholipid synthesis, possibly by activating CDS1 and PI4K2A. This activity requires Tyr-dephosphorylation and association with the endoplasmic reticulum.

    基因ID

    2353

    UniProt

    P01100

    途径

    S100 Proteins
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