CYB5R3 抗体 (AbBy Fluor® 350)
Quick Overview for CYB5R3 抗体 (AbBy Fluor® 350) (ABIN1693370)
抗原
See all CYB5R3 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 小鼠
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预测反应
- Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human CYB5R3
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亚型
- IgG
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anti-Cytochrome B5 Reductase 3 (CYB5R3) (AA 1-301) antibody
CYB5R3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Cytochrome B5 Reductase 3 (CYB5R3) (AA 1-301) antibodyCYB5R3 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome B5 Reductase 3 (CYB5R3) (AA 1-301) antibodyCYB5R3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Cytochrome B5 Reductase 3 (CYB5R3) antibodyCYB5R3 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome B5 Reductase 3 (CYB5R3) (C-Term) antibodyCYB5R3 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cytochrome B5 Reductase 3 (CYB5R3) antibodyCYB5R3 适用: 人, 犬, 猴 WB, IHC, FACS 宿主: 小鼠 Monoclonal 2A10 unconjugated
anti-Cytochrome B5 Reductase 3 (CYB5R3) (AA 111-144) antibodyCYB5R3 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal RB49795 unconjugated
anti-Cytochrome B5 Reductase 3 (CYB5R3) antibody (Biotin)CYB5R3 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal Biotin
anti-Cytochrome B5 Reductase 3 (CYB5R3) (C-Term) antibodyVerified CYB5R3 适用: 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Cytochrome B5 Reductase 3 (CYB5R3) (C-Term) antibodyVerified CYB5R3 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
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应用备注
- IF(IHC-P) 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- CYB5R3 (Cytochrome B5 Reductase 3 (CYB5R3))
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别名
- Cyb5r3
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背景
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Synonyms: B5R, Cyb5r3, Cytochrome b5 reductase 3, Cytochrome b5 reductase, DIA1, Diaphorase 1, Diaphorase-1, NADH cytochrome b5 reductase 3, NADH-cytochrome b5 reductase 3 membrane-bound form, NADH-cytochrome b5 reductase 3 soluble form, NB5R3_HUMAN, OTTHUMP00000028761, OTTHUMP00000198435, OTTHUMP00000198574, OTTHUMP00000198662, OTTHUMP00000198665.
Background: CYB5R3 is a 301 amino acid protein encoded by the human gene CYB5R3. CYB5R3 belongs to the flavoprotein pyridine nucleotide cytochrome reductase family and has two naturally occuring isoforms. Isoform 1 is anchored to the cytoplasmic side of the endoplasmic reticulum membrane and mitochondrion outer membrane, while isoform 2 is the soluble form found in erythrocytes. CYB5R3 is involved in the desaturation and elongation of fatty acids, cholesterol biosynthesis, drug metabolism and, in erythrocytes, methemoglobin reduction. A serine residue at position 117 seems to only be found in persons of African origin. The allele frequency is 0.23 in African Americans. It is not found in Caucasians, Asians, Indo-Aryans or Arabs. This difference seems to have no effect on the enzyme activity. Defects in CYB5R3 are the cause of hereditary methemoglobinemia (HM). There are three forms of this disease: type 1 (HM1), in which the enzyme is only deficient in erythrocytes with a mild cyanosis, type 2 (HM2), in which the enzyme is completely deficient, and type 3 (HM3), where the deficiency is seen in all blood cells. Type 2 is a severe form accompanied by mental retardation and neurological impairment.
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基因ID
- 1727
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途径
- SARS-CoV-2 Protein Interactome
抗原
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