AES 抗体 (AA 21-120) (AbBy Fluor® 350)
Quick Overview for AES 抗体 (AA 21-120) (AbBy Fluor® 350) (ABIN1693243)
抗原
See all AES 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 21-120
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预测反应
- Human,Mouse,Rat,Cow,Sheep,Chicken
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human TLE5/Amino-terminal enhancer of split
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- AES (Amino-terminal Enhancer of Split (AES))
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别名
- TLE5/Amino-terminal enhancer of split
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背景
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Synonyms: Aes 1, Amino-terminal enhancer of split , Aes 2, aes, AES_HUMAN, Aes1, Aes2, Amino Enhancer of Split, Amino terminal enhancer of split, Amino-terminal enhancer of split, Esp 1, Esp1, Gp130 associated protein GAM, Gp130-associated protein GAM, GRG 5, GRG, GRG protein, GRG5, Protein ESP 1, Protein ESP1, Protein GRG, TLE 5, TLE5.
Background: TLE5 is a 197 amino acid nuclear protein that belongs to the TLE family. Expressed predominately in fetal brain, liver, lung, heart and kidney and in adult muscle, TLE5 functions as either a homooligomer or a heterooligomer with other TLE family members and, through this association, dominantly represses the expression of TLE genes. In addition, TLE5 can repress NFkB-regulated gene expression and is thought to play an important role in initiating and maintaining cell differentiation events. Two isoforms of TLE5 exist due to alternative splicing events.
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基因ID
- 166
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途径
- WNT signaling, SARS-CoV-2 Protein Interactome
抗原
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