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CEP57 抗体 (AA 51-150) (AbBy Fluor® 350)

This anti-CEP57 antibody is a 兔 多克隆 antibody detecting CEP57 in IF (cc) 和 IF (p). Suitable for 人.
产品编号 ABIN1692976
发货至: 中国

Quick Overview for CEP57 抗体 (AA 51-150) (AbBy Fluor® 350) (ABIN1692976)

抗原

See all CEP57 抗体
CEP57 (Centrosomal Protein 57kDa (CEP57))

适用

  • 45
  • 3
  • 2
  • 1

宿主

  • 41
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克隆类型

  • 44
  • 1
多克隆

标记

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  • 1
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This CEP57 antibody is conjugated to AbBy Fluor® 350

应用范围

  • 24
  • 20
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  • 12
  • 6
  • 5
  • 5
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Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 8
    • 4
    • 2
    • 2
    • 2
    • 2
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    • 1
    • 1
    AA 51-150

    预测反应

    Human,Mouse,Rat,Dog,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human CEP57

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    CEP57 (Centrosomal Protein 57kDa (CEP57))

    别名

    CEP57

    背景

    Synonyms: Centrosomal protein 57 kDa, Centrosomal protein of 57 kDa, Cep57, Cep57 protein, CEP57_HUMAN, FGF2 interacting protein, FGF2-interacting protein, KIAA0092, MVA2, PIG8, proliferation inducing protein 8, Testis specic protein 57, Testis-specic protein 57, Translokin, TSP57.

    Background: CEP57 (centrosomal protein 57 kDa), also known as PIG8, TSP57 or Translokin, is a 500 amino acid protein that localizes to both the nucleus and the cytoplasm, specifically associating with microtubules at the centrosome. Expressed ubiquitously, CEP57 exists as a homodimer that functions to mediate the mitogenic activity and nuclear translocation of FGF-2, an internalized growth factor, thereby regulating FGF-2 signaling pathways. Additionally, CEP57 is thought to play a role in spermatogenesis, possibly via the indirect regulation of gene expression. Human CEP57 shares 88 % sequence identity with its mouse and bovine orthologs, suggesting a highly conserved role between species. Multiple isoforms of CEP57 exist due to alternative splicing events.

    途径

    M Phase, Maintenance of Protein Location, Protein targeting to Nucleus, Growth Factor Binding
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