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DOK7 抗体 (AA 21-120) (AbBy Fluor® 350)

This AbBy Fluor® 350-conjugated 兔 多克隆 anti-DOK7 antibody specifically detects DOK7 in WB, IF (cc) 和 IF (p). The antibody is reactive with 大鼠 samples.
产品编号 ABIN1692891
发货至: 中国
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Quick Overview for DOK7 抗体 (AA 21-120) (AbBy Fluor® 350) (ABIN1692891)

抗原

See all DOK7 抗体
DOK7 (Docking Protein 7 (DOK7))

适用

  • 32
  • 23
  • 17
大鼠

宿主

  • 45
  • 4
  • 1
  • 1

克隆类型

  • 47
  • 4
多克隆

标记

  • 21
  • 4
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This DOK7 antibody is conjugated to AbBy Fluor® 350

应用范围

  • 40
  • 19
  • 12
  • 12
  • 10
  • 7
  • 7
  • 4
  • 4
  • 3
  • 2
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 8
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-120

    交叉反应

    大鼠

    预测反应

    Human,Mouse,Dog,Cow,Sheep,Pig,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human DOK7

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    DOK7 (Docking Protein 7 (DOK7))

    别名

    DOK7

    背景

    Synonyms: Docking protein 7, DOK 7, DOK7, DOK7_HUMAN, Downstream of tyrosine kinase 7, Protein Dok-7.

    Background: The downstream of kinase family (Dok1-7) are members of a class of docking? proteins that include the tyrosine kinase substrates IRS-1 and Cas, which contain multiple tyrosine residues and putative SH2 binding sites. Based on their similarities, the Dok family of proteins can be divided into three subgroups: Dok-1/2/3, Dok-4/5/6 and Dok-7. Through its interaction with muscle-specific receptor kinase (MuSK), Dok-7 is crucial for neuromuscular synaptogenesis and for MuSK activation. Mice lacking Dok-7 do not form neuromuscular synapses nor acetylcholine receptor clusters. Mutations in the Dok-7 gene can cause congenital myasthenic syndromes (CMA) recessively inherited disorders characterized by muscle weakness.

    途径

    Skeletal Muscle Fiber Development
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