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Glutamate Receptor 1 抗体 (AA 1-389)

This 小鼠 单克隆 anti-Glutamate Receptor 1 antibody (Clone S355-1) specifically detects Glutamate Receptor 1 in WB, IHC, IF 和 ICC. The antibody is reactive with 大鼠 samples.
产品编号 ABIN1686649
发货至: 中国
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Quick Overview for Glutamate Receptor 1 抗体 (AA 1-389) (ABIN1686649)

抗原

See all Glutamate Receptor 1 (GLUR1) 抗体
Glutamate Receptor 1 (GLUR1)

适用

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大鼠

宿主

  • 144
  • 30
  • 1
  • 1
小鼠

克隆类型

  • 116
  • 60
单克隆

标记

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This Glutamate Receptor 1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

克隆位点

S355-1
  • 抗原表位

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    AA 1-389

    特异性

    Detects ~100 kDa. Does not cross-react with GluR2.

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Protein G Purified

    免疫原

    Fusion protein amino acids 1-389 (extracellular N-terminus) of rat GluA1/GluR1

    亚型

    IgG1
  • 应用备注

    • WB (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.

    说明

    1 μg/ml of ABIN1686649 was sufficient for detection of GluA1/GluR1 in 20 μg of mouse brain membrane lysate and assayed by colorimetric immunoblot analysis using goat anti-mouse IgG:HRP as the secondary antibody.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    -20°C
  • 抗原

    Glutamate Receptor 1 (GLUR1)

    别名

    GluR1

    背景

    Glutamic acid is the major excitatory neurotransmitter in the mammalian central nervous system. Glutamate receptors are classified on the basis of their activation by different agonists (1-3). GluR1, human glutamate receptor type 1, is an integral membrane protein that is widely expressed in the human brain. The postsynaptic actions of glutamic acid are mediated by a variety of receptors that are named according to their selective agonists. GluR1 is known to bind a kainate subtype of agonist. It has been found that malfunctioning of the glutamatergic system may result in certain brain disorders and neurodegeneration (3).

    基因ID

    50592

    NCBI登录号

    NP_113796

    UniProt

    P19490

    途径

    PI3K-Akt Signaling
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